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Details on Person The APOA5 gene is transcribed to yield mRNA and the mRNA is ...
| Class:Id | Summation:9605061 |
|---|---|
| _displayName | The APOA5 gene is transcribed to yield mRNA and the mRNA is ... |
| _timestamp | 2018-05-01 18:52:24 |
| created | [InstanceEdit:9605053] Shamovsky, Veronica, 2018-04-06 |
| literatureReference | [LiteratureReference:9607285] The liver X receptor ligand T0901317 down-regulates APOA5 gene expression through activation of SREBP-1c |
| modified | [InstanceEdit:9607281] Shamovsky, Veronica, 2018-05-01 |
| text | The APOA5 gene is transcribed to yield mRNA and the mRNA is translated to yield protein. A synthetic agonist of liver X receptor (LXR or NR1H2,3), T0901317, decreased APOA5 mRNA levels in human liver cancer HepG2 and HuH7 cells. In addition, promoter analysis showed that APOA5 promoter activity is directly regulated by SREBP1-c, a target of NR1H2,3, but not by NR1H2,3 itself (Jakel H et al. 2004). |
| (summation) | [BlackBoxEvent:9605055] Expression of APOA5 regulated by NR1H2 or NR1H3 [Homo sapiens] |
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No pathways have been reviewed or authored by The APOA5 gene is transcribed to yield mRNA and the mRNA is ... (9605061)
