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Details on Person The protein tyrosine phosphatase, Shp2, positively contributes to FLT3-ITD-induced hematopoietic progenitor hyperproliferation and malignant disease in vivo
| Class:Id | LiteratureReference:9604970 |
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| _displayName | The protein tyrosine phosphatase, Shp2, positively contributes to FLT3-ITD-induced hematopoietic progenitor hyperproliferation and malignant disease in vivo |
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| _timestamp | 2018-04-06 10:37:13 |
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| author | [Person:9604981] Nabinger, S C
[Person:9604986] Li, X J
[Person:9604975] Ramdas, B
[Person:6800083] He, Y
[Person:2500267] Zhang, X
[Person:2424445] Zeng, L
[Person:9604983] Richine, B
[Person:9604979] Bowling, J D
[Person:2458287] Fukuda, S
[Person:9604976] Goenka, S
[Person:72748] Liu, Z
[Person:9604974] Feng, G-S
[Person:5359383] Yu, M
[Person:9604985] Sandusky, G E
[Person:9604973] Boswell, H S
[Person:9604984] Zhang, Z-Y
[Person:5668672] Kapur, R
[Person:9604982] Chan, R J |
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| created | [InstanceEdit:9604971] Varusai, Thawfeek, 2018-04-06 |
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| journal | Leukemia |
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| modified | [InstanceEdit:9604991] Varusai, Thawfeek, 2018-04-06 |
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| pages | 398-408 |
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| pubMedIdentifier | 23103841 |
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| title | The protein tyrosine phosphatase, Shp2, positively contributes to FLT3-ITD-induced hematopoietic progenitor hyperproliferation and malignant disease in vivo |
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| volume | 27 |
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| year | 2013 |
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| (literatureReference) | [Reaction:9604969] Active FLT3 binds PTPN11 [Homo sapiens]
[Reaction:9604980] Active Flt3 binds Ptpn11 [Mus musculus]
[Reaction:9645126] Activators bind STAT5 [Homo sapiens]
[Reaction:9645128] Activators bind Stat5 [Mus musculus]
[Reaction:9645133] p-Stat5 dissociates from activator:Stat5 complex [Mus musculus]
[Reaction:9645134] p-STAT5 dissociates from activator:STAT5 complex [Homo sapiens]
[Pathway:9645135] STAT5 Activation [Homo sapiens]
[Reaction:9645136] Activator phosphorylates Stat5 [Mus musculus]
[Reaction:9645137] Activator phosphorylates STAT5 [Homo sapiens]
[Reaction:9698005] FLT3 ITD mutants phosphorylate STAT5 [Homo sapiens] |
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