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Details on Person Sirt6 [nucleoplasm]

Class:Id	EntityWithAccessionedSequence:9604878
_displayName	Sirt6 [nucleoplasm]
_timestamp	2018-04-05 17:50:12
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9604880] Orlic-Milacic, Marija, 2018-04-05
endCoordinate	334
name	Sirt6 NAD-dependent protein deacetylase sirtuin-6 ecNumber3.5.1.-/ecNumber SIR6_MOUSE
referenceEntity	[ReferenceGeneProduct:101630] UniProt:P59941 Sirt6 [Mus musculus]
species	[Species:48892] Mus musculus
stableIdentifier	[StableIdentifier:9604885] R-MMU-9604878.1
startCoordinate	2
(activeUnit)	[CatalystActivity:9604917] histone H3K9 deacetylase activity, NAD-dependent of Sirt6:Nucleosome(H3K9ac):Notch1,Notch4 gene [nucleoplasm] [NegativeGeneExpressionRegulation:9604933] Negative gene expression regulation by 'Sirt6:Nucleosome:Notch1,Notch4 gene [nucleoplasm]'
(hasComponent)	[Complex:9604891] Sirt6:Nucleosome(H3K9ac):Notch1 gene [nucleoplasm] [Mus musculus] [Complex:9604893] Sirt6:Nucleosome(H3K9ac):Notch4 gene [nucleoplasm] [Mus musculus] [Complex:9604904] Sirt6:Nucleosome:Notch1 gene [nucleoplasm] [Mus musculus] [Complex:9604907] Sirt6:Nucleosome:Notch4 gene [nucleoplasm] [Mus musculus]
(input)	[Reaction:9604828] Sirt6 binds to acetylated histones at Notch1 and Notch4 gene promoters [Mus musculus]
(physicalEntity)	[CatalystActivity:9961121] NAD-dependent protein lysine deacetylase activity of Sirt6 [nucleoplasm]
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No pathways have been reviewed or authored by Sirt6 [nucleoplasm] (9604878)