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Details on Person Identification of Y589 and Y599 in the juxtamembrane domain of Flt3 as ligand-induced autophosphorylation sites involved in binding of Src family kinases and the protein tyrosine phosphatase SHP2
| Class:Id | LiteratureReference:9604777 |
| _displayName | Identification of Y589 and Y599 in the juxtamembrane domain of Flt3 as ligand-induced autophosphorylation sites involved in binding of Src family kinases and the protein tyrosine phosphatase SHP2 |
| _timestamp | 2018-07-13 17:53:26 |
| author | [Person:9604746] Heiss, Elke [Person:9604782] Masson, Kristina [Person:9604742] Sundberg, Christina [Person:9604779] Pedersen, Malin [Person:9604745] Sun, Jianmin [Person:9604747] Bengtsson, Susanne [Person:9606963] Rönnstrand, Lars |
| created | [InstanceEdit:9604761] Varusai, Thawfeek, 2018-04-05 |
| journal | Blood |
| modified | [InstanceEdit:9604817] Varusai, Thawfeek, 2018-04-05 [InstanceEdit:9613372] D'Eustachio, Peter, 2018-07-13 |
| pages | 1542-50 |
| pubMedIdentifier | 16684964 |
| title | Identification of Y589 and Y599 in the juxtamembrane domain of Flt3 as ligand-induced autophosphorylation sites involved in binding of Src family kinases and the protein tyrosine phosphatase SHP2 |
| volume | 108 |
| year | 2006 |
| (literatureReference) | [BlackBoxEvent:9604767] FLT3LG dimer:FLT3 dimer autophosphorylates [Homo sapiens] [Reaction:9604969] Active FLT3 binds PTPN11 [Homo sapiens] [Reaction:9604980] Active Flt3 binds Ptpn11 [Mus musculus] [BlackBoxEvent:9609272] Active Flt3 binds Hck [Mus musculus] [BlackBoxEvent:9609274] Active FLT3 binds HCK [Homo sapiens] [Reaction:9695841] FLT3 mutant dimers bind GRB2 [Homo sapiens] [Reaction:9698007] FLT3 ITD mutants bind STAT5 through GAB2:PTPN11 [Homo sapiens] [Reaction:9698008] FLT3 mutants:GRB2:p-Y-GAB2 binds PTPN11 [Homo sapiens] [Reaction:9698021] PTPN11:p-STAT5 binds BCL2L1 promoter [Homo sapiens] [Reaction:9706293] Active FLT3 binds to CBL [Homo sapiens] |
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