Reactome: A Curated Pathway Database
THIS SITE IS USED FOR CURATION AND TESTING
IT IS NOT STABLE, IS LINKED TO AN INCOMPLETE DATA SET, AND IS NOT MONITORED FOR PERFORMANCE. WE STRONGLY RECOMMEND THE USE OF OUR PUBLIC SITE

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Name Email address

Details on Person Identification of Y589 and Y599 in the juxtamembrane domain of Flt3 as ligand-induced autophosphorylation sites involved in binding of Src family kinases and the protein tyrosine phosphatase SHP2

Class:IdLiteratureReference:9604777
_displayNameIdentification of Y589 and Y599 in the juxtamembrane domain of Flt3 as ligand-induced autophosphorylation sites involved in binding of Src family kinases and the protein tyrosine phosphatase SHP2
_timestamp2018-07-13 17:53:26
author[Person:9604746] Heiss, Elke
[Person:9604782] Masson, Kristina
[Person:9604742] Sundberg, Christina
[Person:9604779] Pedersen, Malin
[Person:9604745] Sun, Jianmin
[Person:9604747] Bengtsson, Susanne
[Person:9606963] Rönnstrand, Lars
created[InstanceEdit:9604761] Varusai, Thawfeek, 2018-04-05
journalBlood
modified[InstanceEdit:9604817] Varusai, Thawfeek, 2018-04-05
[InstanceEdit:9613372] D'Eustachio, Peter, 2018-07-13
pages1542-50
pubMedIdentifier16684964
titleIdentification of Y589 and Y599 in the juxtamembrane domain of Flt3 as ligand-induced autophosphorylation sites involved in binding of Src family kinases and the protein tyrosine phosphatase SHP2
volume108
year2006
(literatureReference)[BlackBoxEvent:9604767] FLT3LG dimer:FLT3 dimer autophosphorylates [Homo sapiens]
[Reaction:9604969] Active FLT3 binds PTPN11 [Homo sapiens]
[Reaction:9604980] Active Flt3 binds Ptpn11 [Mus musculus]
[BlackBoxEvent:9609272] Active Flt3 binds Hck [Mus musculus]
[BlackBoxEvent:9609274] Active FLT3 binds HCK [Homo sapiens]
[Reaction:9695841] FLT3 mutant dimers bind GRB2 [Homo sapiens]
[Reaction:9698007] FLT3 ITD mutants bind STAT5 through GAB2:PTPN11 [Homo sapiens]
[Reaction:9698008] FLT3 mutants:GRB2:p-Y-GAB2 binds PTPN11 [Homo sapiens]
[Reaction:9698021] PTPN11:p-STAT5 binds BCL2L1 promoter [Homo sapiens]
[Reaction:9706293] Active FLT3 binds to CBL [Homo sapiens]
List all 12 refering instances
[Change default viewing format]
No pathways have been reviewed or authored by Identification of Y589 and Y599 in the juxtamembrane domain of Flt3 as ligand-induced autophosphorylation sites involved in binding of Src family kinases and the protein tyrosine phosphatase SHP2 (9604777)