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Details on Person Direct binding of Grb2 has an important role in the development of myeloproliferative disease induced by ETV6/FLT3

Class:IdLiteratureReference:9604770
_displayNameDirect binding of Grb2 has an important role in the development of myeloproliferative disease induced by ETV6/FLT3
_timestamp2018-04-05 15:00:56
author[Person:9604763] Chonabayashi, K
[Person:9604773] Hishizawa, M
[Person:9604766] Kawamata, S
[Person:8869426] Nagai, Y
[Person:9604744] Ohno, T
[Person:2682358] Ishikawa, T
[Person:9604759] Uchiyama, T
[Person:9604758] Takaori-Kondo, A
created[InstanceEdit:9604761] Varusai, Thawfeek, 2018-04-05
journalLeukemia
modified[InstanceEdit:9604817] Varusai, Thawfeek, 2018-04-05
pages1433-6
pubMedIdentifier23168613
titleDirect binding of Grb2 has an important role in the development of myeloproliferative disease induced by ETV6/FLT3
volume27
year2013
(literatureReference)[EntityWithAccessionedSequence:9696032] FLT3 R595_L601dup [plasma membrane] [Homo sapiens]
[EntityWithAccessionedSequence:9697944] ETV6(1-384)-FLT3(569-993) fusion [cytosol] [Homo sapiens]
[CandidateSet:9697968] p-6Y FLT3 ITD mutant dimers [plasma membrane] [Homo sapiens]
[EntityWithAccessionedSequence:9703313] ETV6(1-384)-p-3Y-FLT3(659-1620) fusion [cytosol] [Homo sapiens]
[CandidateSet:9703345] FLT3 fusion proteins [cytosol] [Homo sapiens]
[Complex:9703378] p-Y FLT3 fusion dimers:GRB2 [cytosol] [Homo sapiens]
[Reaction:9604738] Active FLT3 dimer binds GRB2 [Homo sapiens]
[Reaction:9604768] Active Flt3 dimer binds Grb2 [Mus musculus]
[BlackBoxEvent:9606621] Gab2 in Active Flt3:Grb2:Gab2 is phosphorylated [Mus musculus]
[BlackBoxEvent:9606622] GAB2 in Active FLT3:GRB2:GAB2 is phosphorylated [Homo sapiens]
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No pathways have been reviewed or authored by Direct binding of Grb2 has an important role in the development of myeloproliferative disease induced by ETV6/FLT3 (9604770)