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Details on Person Active FLT3 [plasma membrane]

Class:Id	Complex:9604751
_displayName	Active FLT3 [plasma membrane]
_timestamp	2019-01-16 13:54:14
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:9604761] Varusai, Thawfeek, 2018-04-05
hasComponent	[Complex:8854740] FLT3LG dimer [extracellular region] [Homo sapiens] [EntityWithAccessionedSequence:6786793] FLT3LG [extracellular region] [Homo sapiens] [EntityWithAccessionedSequence:6786793] FLT3LG [extracellular region] [Homo sapiens] [EntityWithAccessionedSequence:9604780] Autophosphorylated FLT3 [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:9604780] Autophosphorylated FLT3 [plasma membrane] [Homo sapiens]
isChimeric	FALSE
modified	[InstanceEdit:9604817] Varusai, Thawfeek, 2018-04-05 [InstanceEdit:9604971] Varusai, Thawfeek, 2018-04-06 [InstanceEdit:9634820] Varusai, Thawfeek, 2019-01-16
name	Active FLT3
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9604787] R-HSA-9604751.2
(hasComponent)	[Complex:9604756] Active FLT3: GRB2 [plasma membrane] [Homo sapiens] [Complex:9604972] Active FLT3:PTPN11 [plasma membrane] [Homo sapiens] [Complex:9605257] Active FLT3:FYN [plasma membrane] [Homo sapiens] [Complex:9609280] Active FLT3:HCK [plasma membrane] [Homo sapiens] [Complex:9706224] active FLT3:pY-CBL [plasma membrane] [Homo sapiens] [Complex:9706226] active FLT3:SOCS2 [plasma membrane] [Homo sapiens] [Complex:9706227] active FLT3:SOCS6 [plasma membrane] [Homo sapiens] [Complex:9706233] Active FLT3:CBL mutants [plasma membrane] [Homo sapiens] [Complex:9706249] active FLT3:ABL2 [plasma membrane] [Homo sapiens] [Complex:9706252] active FLT3:CBL [plasma membrane] [Homo sapiens] List all 21 refering instances
(input)	[Reaction:9604738] Active FLT3 dimer binds GRB2 [Homo sapiens] [Reaction:9604969] Active FLT3 binds PTPN11 [Homo sapiens] [Reaction:9605259] Active FLT3 binds FYN [Homo sapiens] [BlackBoxEvent:9609274] Active FLT3 binds HCK [Homo sapiens] [Reaction:9698408] PTPRJ dephosphorylates active FLT3 [Homo sapiens] [Reaction:9706287] Active FLT3 binds to ABL2 [Homo sapiens] [Reaction:9706293] Active FLT3 binds to CBL [Homo sapiens] [Reaction:9706298] Active FLT3 binds to CSK [Homo sapiens] [Reaction:9706304] Active FLT3 binds to GRAP2 [Homo sapiens] [Reaction:9706308] Active FLT3 binds to GRB10 [Homo sapiens] List all 19 refering instances
(normalEntity)	[EntityFunctionalStatus:9698197] gain_of_function of p-6Y FLT3 extracellular domain, kinase domain and juxtamembrane domain mutant dimers [plasma membrane]
(output)	[BlackBoxEvent:9604767] FLT3LG dimer:FLT3 dimer autophosphorylates [Homo sapiens]
(physicalEntity)	[CatalystActivity:9699580] protein tyrosine kinase activity of Active FLT3 [plasma membrane]
(updatedInstance)	[_UpdateTracker:9900243] Update Tracker - [Complex:9604751] Active FLT3 [plasma membrane] - v68:[modifyName]
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No pathways have been reviewed or authored by Active FLT3 [plasma membrane] (9604751)