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Details on Person ACTA2 gene expression is stimulated by NOTCH1, NOTCH2 and NOTCH4

Class:Id	BlackBoxEvent:9604664
_displayName	ACTA2 gene expression is stimulated by NOTCH1, NOTCH2 and NOTCH4
_doRelease	TRUE
_timestamp	2018-05-09 14:10:41
authored	[InstanceEdit:9604946] Orlic-Milacic, Marija, 2018-04-05
compartment	[Compartment:7660] nucleoplasm [Compartment:70101] cytosol
created	[InstanceEdit:9604667] Orlic-Milacic, Marija, 2018-04-04
edited	[InstanceEdit:9608067] Orlic-Milacic, Marija, 2018-05-09
goBiologicalProcess	[GO_BiologicalProcess:17789] positive regulation of DNA-templated transcription
input	[EntityWithAccessionedSequence:8957900] ACTA2 gene [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:9604663] Hairy-related transcription factors inhibit Notch-induced smooth muscle alpha-actin expression by interfering with Notch intracellular domain/CBF-1 complex interaction with the CBF-1-binding site
modified	[InstanceEdit:9605470] Orlic-Milacic, Marija, 2018-04-11 [InstanceEdit:9606200] Wu, G, 2018-04-19 [InstanceEdit:9608068] Orlic-Milacic, Marija, 2018-05-09 [InstanceEdit:9608071] Orlic-Milacic, Marija, 2018-05-09 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	ACTA2 gene expression is stimulated by NOTCH1, NOTCH2 and NOTCH4
output	[EntityWithAccessionedSequence:445792] ACTA2 [cytosol] [Homo sapiens]
precedingEvent	[Reaction:9013693] NICD4 binds RBPJ and MAML in the nucleus [Homo sapiens]
regulatedBy	[PositiveRegulation:9604662] Positive regulation by 'NOTCH1,NOTCH2,NOTCH4 coactivator complex [nucleoplasm]'
releaseDate	2018-06-12
reviewed	[InstanceEdit:9608066] Haw, Robin, 2018-05-01
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9604671] R-HSA-9604664.2
summation	[Summation:9604669] ACTA2 gene, encoding smooth muscle alpha actin, possesses se...
(hasEvent)	[Pathway:9013695] NOTCH4 Intracellular Domain Regulates Transcription [Homo sapiens]
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No pathways have been reviewed or authored by ACTA2 gene expression is stimulated by NOTCH1, NOTCH2 and NOTCH4 (9604664)