Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Details on Person FBXW7 promotes ubiquitination of p-NICD4

Class:Id	Reaction:9604629
_displayName	FBXW7 promotes ubiquitination of p-NICD4
_doRelease	TRUE
_timestamp	2018-05-09 14:10:42
authored	[InstanceEdit:9604946] Orlic-Milacic, Marija, 2018-04-05
catalystActivity	[CatalystActivity:9604630] ubiquitin protein ligase activity of FBXW7:SKP1:CUL1:RBX1 [nucleoplasm]
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9604626] Orlic-Milacic, Marija, 2018-04-04
edited	[InstanceEdit:9608067] Orlic-Milacic, Marija, 2018-05-09
inferredFrom	[Reaction:9604628] FBXW7 promotes ubiquitination of mouse p-NICD4 [Homo sapiens]
input	[EntityWithAccessionedSequence:9604611] p-NICD4 [nucleoplasm] [Homo sapiens] [DefinedSet:68524] Ub [nucleoplasm] [Homo sapiens] [DefinedSet:68524] Ub [nucleoplasm] [Homo sapiens] [DefinedSet:68524] Ub [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
modified	[InstanceEdit:9604644] Orlic-Milacic, Marija, 2018-04-04 [InstanceEdit:9608068] Orlic-Milacic, Marija, 2018-05-09 [InstanceEdit:9608071] Orlic-Milacic, Marija, 2018-05-09 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	FBXW7 promotes ubiquitination of p-NICD4
output	[EntityWithAccessionedSequence:9604624] PolyUb-p-NICD4 [nucleoplasm] [Homo sapiens]
precedingEvent	[BlackBoxEvent:9604606] Unknown kinase phosphorylates NICD4 [Homo sapiens] [BlackBoxEvent:9604308] NICD4 traffics to the nucleus [Homo sapiens]
releaseDate	2018-06-12
reviewed	[InstanceEdit:9608066] Haw, Robin, 2018-05-01
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9604631] R-HSA-9604629.2
summation	[Summation:9604627] The E3 ubiquitin ligase FBXW7, a component of the SCF ubiqui...
(hasEvent)	[Pathway:9604323] Negative regulation of NOTCH4 signaling [Homo sapiens]
(precedingEvent)	[BlackBoxEvent:9604642] Proteasome degrades ubiquitinated NICD4 [Homo sapiens]
[Change default viewing format]

No pathways have been reviewed or authored by FBXW7 promotes ubiquitination of p-NICD4 (9604629)