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Details on Person FBXW7 promotes ubiquitination of mouse p-NICD4

Class:Id	Reaction:9604628
_displayName	FBXW7 promotes ubiquitination of mouse p-NICD4
_doRelease	TRUE
_timestamp	2018-05-09 14:10:42
authored	[InstanceEdit:9604946] Orlic-Milacic, Marija, 2018-04-05
catalystActivity	[CatalystActivity:9604630] ubiquitin protein ligase activity of FBXW7:SKP1:CUL1:RBX1 [nucleoplasm]
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9604626] Orlic-Milacic, Marija, 2018-04-04
edited	[InstanceEdit:9608067] Orlic-Milacic, Marija, 2018-05-09
input	[EntityWithAccessionedSequence:9604620] p-NICD4 [nucleoplasm] [Mus musculus] [CandidateSet:517940] Ubiquitin [nucleoplasm] [Mus musculus] [CandidateSet:517940] Ubiquitin [nucleoplasm] [Mus musculus] [CandidateSet:517940] Ubiquitin [nucleoplasm] [Mus musculus]
isChimeric	TRUE
literatureReference	[LiteratureReference:2064869] SEL-10 is an inhibitor of notch signaling that targets notch for ubiquitin-mediated protein degradation
modified	[InstanceEdit:9604640] Orlic-Milacic, Marija, 2018-04-04 [InstanceEdit:9604644] Orlic-Milacic, Marija, 2018-04-04 [InstanceEdit:9608068] Orlic-Milacic, Marija, 2018-05-09 [InstanceEdit:9608069] Orlic-Milacic, Marija, 2018-05-09 [InstanceEdit:9608071] Orlic-Milacic, Marija, 2018-05-09 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	FBXW7 promotes ubiquitination of mouse p-NICD4
output	[EntityWithAccessionedSequence:9604638] PolyUb-p-NICD4 [nucleoplasm] [Mus musculus]
releaseDate	2018-06-12
reviewed	[InstanceEdit:9608066] Haw, Robin, 2018-05-01
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens [Species:48892] Mus musculus
stableIdentifier	[StableIdentifier:9604633] R-NUL-9604628.2
summation	[Summation:9604637] The human E3 ubiquitin ligase FBXW7, a component of the SCF ...
(inferredFrom)	[Reaction:9604629] FBXW7 promotes ubiquitination of p-NICD4 [Homo sapiens]
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No pathways have been reviewed or authored by FBXW7 promotes ubiquitination of mouse p-NICD4 (9604628)