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Details on Person The NOTCH4 coactivator complex, composed of NICD4 (NOTCH4 in...
| Class:Id | Summation:9604450 |
|---|---|
| _displayName | The NOTCH4 coactivator complex, composed of NICD4 (NOTCH4 in... |
| _timestamp | 2018-04-03 16:41:50 |
| created | [InstanceEdit:9604448] Orlic-Milacic, Marija, 2018-04-03 |
| literatureReference | [LiteratureReference:9604193] Notch alters VEGF responsiveness in human and murine endothelial cells by direct regulation of VEGFR-3 expression |
| modified | [InstanceEdit:9604470] Orlic-Milacic, Marija, 2018-04-03 [InstanceEdit:9604477] Orlic-Milacic, Marija, 2018-04-03 |
| text | The NOTCH4 coactivator complex, composed of NICD4 (NOTCH4 intracellular domain fragment), RBPJ (CSL) and one of mastermind proteins, MAML1, MAML2 or MAML3, binds to CSL response elements in the promoter of the FLT4 (VEGFR3) gene, encoding Vascular endothelial growth factor receptor-3 (Shawber et al. 2007). |
| (summation) | [Reaction:9604451] NOTCH4 binds FLT4 gene promoter [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by The NOTCH4 coactivator complex, composed of NICD4 (NOTCH4 in... (9604450)
