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Details on Person NICD4 traffics to the nucleus

Class:IdBlackBoxEvent:9604308
_displayNameNICD4 traffics to the nucleus
_doReleaseTRUE
_timestamp2018-05-09 14:42:48
authored[InstanceEdit:157021] Jassal, B, 2004-12-15 13:08:03
[InstanceEdit:9604946] Orlic-Milacic, Marija, 2018-04-05
compartment[Compartment:13231] nuclear envelope
created[InstanceEdit:9604307] Orlic-Milacic, Marija, 2018-04-02
edited[InstanceEdit:9608067] Orlic-Milacic, Marija, 2018-05-09
goBiologicalProcess[GO_BiologicalProcess:24616] positive regulation of Notch signaling pathway
input[EntityWithAccessionedSequence:157636] NICD4 [cytosol] [Homo sapiens]
literatureReference[LiteratureReference:9604316] AKT and 14-3-3 regulate Notch4 nuclear localization
modified[InstanceEdit:9604322] Orlic-Milacic, Marija, 2018-04-02
[InstanceEdit:9604327] Orlic-Milacic, Marija, 2018-04-02
[InstanceEdit:9606200] Wu, G, 2018-04-19
[InstanceEdit:9608068] Orlic-Milacic, Marija, 2018-05-09
[InstanceEdit:9608071] Orlic-Milacic, Marija, 2018-05-09
[InstanceEdit:9608080] Orlic-Milacic, Marija, 2018-05-09
[InstanceEdit:9608089] Orlic-Milacic, Marija, 2018-05-09
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameNICD4 traffics to the nucleus
output[EntityWithAccessionedSequence:157945] NICD4 [nucleoplasm] [Homo sapiens]
precedingEvent
regulatedBy[NegativeRegulation:9604397] Negative regulation by 'p-4S-NICD4:YWHAZ dimer [cytosol]'
releaseDate2005-06-12
reviewed[InstanceEdit:165114] Joutel, A, 2004-12-15
[InstanceEdit:9608066] Haw, Robin, 2018-05-01
reviewStatus[ReviewStatus:9821382] five stars
revised[InstanceEdit:9604946] Orlic-Milacic, Marija, 2018-04-05
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9604309] R-HSA-9604308.2
summation[Summation:178977] The cytosolic NICD4 translocates to the nucleus. Trafficking...
(hasEvent)[Pathway:9013700] NOTCH4 Activation and Transmission of Signal to the Nucleus [Homo sapiens]
(precedingEvent)[BlackBoxEvent:9604606] Unknown kinase phosphorylates NICD4 [Homo sapiens]
(replacementInstances)[_Deleted:9608083] Deletion of instance: 157941
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