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Details on Person Expression of NLRP3 gene

Class:IdBlackBoxEvent:9603905
_displayNameExpression of NLRP3 gene
_doReleaseTRUE
_timestamp2018-03-29 08:06:47
authored[InstanceEdit:9603904] Jassal, Bijay, 2018-03-28
compartment[Compartment:7660] nucleoplasm
[Compartment:70101] cytosol
created[InstanceEdit:9603904] Jassal, Bijay, 2018-03-28
edited[InstanceEdit:9603904] Jassal, Bijay, 2018-03-28
input[EntityWithAccessionedSequence:9603902] NLRP3 gene [nucleoplasm] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:844628] Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression
[LiteratureReference:9603924] Molecular mechanisms regulating NLRP3 inflammasome activation
modified[InstanceEdit:9603916] Jassal, Bijay, 2018-03-28
[InstanceEdit:9603978] Jassal, Bijay, 2018-03-29
[InstanceEdit:9606200] Wu, G, 2018-04-19
[InstanceEdit:9641190] Wu, G, 2019-04-04
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameExpression of NLRP3 gene
output[EntityWithAccessionedSequence:561189] NLRP3 [cytosol] [Homo sapiens]
regulatedBy[PositiveRegulation:9603907] Positive regulation by 'NFkB Complex [nucleoplasm]'
regulationReference[RegulationReference:9642076] Positive regulation by 'NFkB Complex [nucleoplasm]' Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression
releaseDate2018-06-12
reviewed[InstanceEdit:9603977] Jo, Eun-Kyeong, 2018-03-29
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9603906] R-HSA-9603905.3
summation[Summation:9603917] Two signals are required for NLRP3 inflammasome activation. ...
(hasEvent)[Pathway:844456] The NLRP3 inflammasome [Homo sapiens]
[Pathway:9660826] Purinergic signaling in leishmaniasis infection [Homo sapiens]
(precedingEvent)[Reaction:1250272] TXNIP binds NLRP3 [Homo sapiens]
(updatedInstance)[_UpdateTracker:9775990] Update Tracker - [BlackBoxEvent:9603905] Expression of NLRP3 gene - v78:[modifyText]
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No pathways have been reviewed or authored by Expression of NLRP3 gene (9603905)