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Details on Person Factor IIa inhibitors (peptide) bind IIa

Class:Id	Reaction:9603302
_displayName	Factor IIa inhibitors (peptide) bind IIa
_doRelease	TRUE
_timestamp	2025-02-18 10:18:15
authored	[InstanceEdit:9603317] Jassal, Bijay, 2018-03-19
compartment	[Compartment:984] extracellular region
created	[InstanceEdit:9603317] Jassal, Bijay, 2018-03-19
edited	[InstanceEdit:9603317] Jassal, Bijay, 2018-03-19
input	[Complex:156786] activated thrombin (factor IIa) [extracellular region] [Homo sapiens] [DefinedSet:9603327] Factor IIa inhibitors (peptide) [extracellular region]
isChimeric	FALSE
literatureReference	[LiteratureReference:9603314] Clot-bound thrombin is protected from inhibition by heparin-antithrombin III but is susceptible to inactivation by antithrombin III-independent inhibitors [LiteratureReference:9603309] Bivalirudin: a direct thrombin inhibitor [LiteratureReference:9603304] Desirudin: a review of the pharmacology and clinical application for the prevention of deep vein thrombosis
modified	[InstanceEdit:9603354] Jassal, Bijay, 2018-03-21 [InstanceEdit:9603359] Jassal, Bijay, 2018-03-21 [InstanceEdit:9696624] Jassal, Bijay, 2020-07-23 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9938577] Shamovsky, Veronica, 2025-02-18
name	Factor IIa inhibitors (peptide) bind IIa
output	[Complex:9603322] Factor IIa inhibitors (peptide):IIa [extracellular region] [Homo sapiens]
releaseDate	2018-06-12
reviewed	[InstanceEdit:9603358] G�mez-Outes, Antonio, 2018-03-21
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9603329] R-HSA-9603302.4
summation	[Summation:9603298] In the blood coagulation process, prothrombin is proteolytic...
(hasEvent)	[Pathway:140837] OBSOLETE_Intrinsic Pathway of Fibrin Clot Formation_REPLACEMENT_9769743_9970672 [Homo sapiens] [Pathway:9769739] Regulation of clotting cascade [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9939828] Update Tracker - [Reaction:9603302] Factor IIa inhibitors (peptide) bind IIa - v92:[modifyText]
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No pathways have been reviewed or authored by Factor IIa inhibitors (peptide) bind IIa (9603302)