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Details on Person Transport of glycoproteins with Man8 (or Man9) N-glycans to the Golgi

Class:Id	Reaction:947991
_displayName	Transport of glycoproteins with Man8 (or Man9) N-glycans to the Golgi
_doRelease	TRUE
_timestamp	2015-05-29 18:04:23
authored	[InstanceEdit:749521] Dall'Olio, GM, 2009-11-10
catalystActivity	[CatalystActivity:1017218] D-mannose binding activity of LMAN1:MCFD2 [ER to Golgi transport vesicle membrane]
compartment	[Compartment:927893] endoplasmic reticulum quality control compartment [Compartment:17963] Golgi lumen
created	[InstanceEdit:948003] Jassal, B, 2010-09-15
edited	[InstanceEdit:948003] Jassal, B, 2010-09-15
input	[DefinedSet:948002] Glycoproteins with Man8 N-glycans [endoplasmic reticulum quality control compartment] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:1029606] The cargo receptor ERGIC-53 is a target of the unfolded protein response [LiteratureReference:947994] Bleeding due to disruption of a cargo-specific ER-to-Golgi transport complex
modified	[InstanceEdit:948030] Jassal, B, 2010-09-15 [InstanceEdit:1008193] Jassal, B, 2010-11-10 [InstanceEdit:1017217] Jassal, B, 2010-11-16 [InstanceEdit:1022097] Jassal, B, 2010-11-17 [InstanceEdit:1022125] Jassal, B, 2010-11-17 [InstanceEdit:1028800] Jassal, B, 2010-11-18 [InstanceEdit:1029696] Jassal, B, 2010-11-18 [InstanceEdit:1030020] Jassal, B, 2010-11-18 [InstanceEdit:5696640] Matthews, Lisa, 2015-05-29 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Transport of glycoproteins with Man8 (or Man9) N-glycans to the Golgi
output	[DefinedSet:948022] Glycoproteins with Man8 N-glycans [Golgi lumen] [Homo sapiens]
precedingEvent	[Reaction:901024] MAN1B1 hydrolyses 1,2-linked mannose (a branch) [Homo sapiens] [Reaction:901074] MAN1B1,EDEM2 hydrolyse 1,2-linked mannose (b branch) [Homo sapiens] [Reaction:912291] Incorrectly folded glycoproteins translocate to the ERQC [Homo sapiens] [Reaction:901039] MAN1B1 hydrolyses 1,2-linked mannose (c branch) [Homo sapiens]
releaseDate	2010-12-14
reviewed	[InstanceEdit:1028799] Gagneux, P, 2010-11-18
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:1105067] R-HSA-947991.3
summation	[Summation:948000] The LMAN1(also known as ERGIC-53)/MCFD2 complex recognizes M...
(hasEvent)	[Pathway:948021] Transport to the Golgi and subsequent modification [Homo sapiens]
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