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Details on Person NF1 binds to Ras:GTP complex

Class:IdReaction:947786
_displayNameNF1 binds to Ras:GTP complex
_timestamp2016-07-15 23:49:49
authored[InstanceEdit:947710] Williams, MG, 2010-09-09
compartment[Compartment:70101] cytosol
created[InstanceEdit:947774] Williams, MG, 2010-09-13
figure[Figure:947943] /figures/DrosRasRafERKA14.jpg
input[Complex:947802] N-Ras:GTP [cytosol] [Homo sapiens]
[EntityWithAccessionedSequence:947770] NF1(2-2839) [cytosol] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:947794] Kinetics of interaction between normal and proline 12 Ras and the GTPase-activating proteins, p120-GAP and neurofibromin. The significance of the intrinsic GTPase rate in determining the transforming ability of ras
[LiteratureReference:947764] Individual rate constants for the interaction of Ras proteins with GTPase-activating proteins determined by fluorescence spectroscopy
[LiteratureReference:947796] The mechanism of Ras GTPase activation by neurofibromin
modified[InstanceEdit:947989] Williams, MG, 2010-09-14
[InstanceEdit:8879177] Wu, G, 2016-07-15
nameNF1 binds to Ras:GTP complex
output[Complex:947776] NF1:N-Ras:GTP [cytosol] [Homo sapiens]
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:8904561] R-HSA-947786.1
summation[Summation:947791] In humans, the GTPase activating protein, Neurofibromin 1 (N...
(hasEvent)[Pathway:481001] Ras/Raf/ERK pathway - Inferred Events
(inferredFrom)[Reaction:947782] NF1 binds to RAS85D:GTP complex [Drosophila melanogaster]
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