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Details on Person UniProt:O59751 klp6
Class:Id
ReferenceGeneProduct:93976
_chainChangeLog
chain:1-784 added on Fri February 6 2015
_displayName
UniProt:O59751 klp6
_timestamp
2024-02-26 04:24:35
chain
chain:1-784
checksum
EBE985FF79C18BB6
comment
FUNCTION Has a role in establishing metaphase during mitosis. Required for chromosome segregation where it generates tension during kinetochore capturing.SUBUNIT Heterodimer with klp5.INTERACTION Cytoplasmic microtubules in interphase, mitotic kinetochores in metaphase and spindle midzone in anaphase and telophase.DISRUPTION PHENOTYPE Simultaneous disruption of dam1 is lethal and leads to the cut phenotype (septation without chromosome segregation).SIMILARITY Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. Kinesin II subfamily.
