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Details on Person UniProt:Q9JJZ6 Klf13

Class:IdReferenceGeneProduct:93949
_chainChangeLogchain:1-289 added on Fri February 6 2015
_displayNameUniProt:Q9JJZ6 Klf13
_timestamp2024-08-09 19:40:23
chainchain:1-289
checksumE248EF12890DA090
commentFUNCTION Transcription factor that activates expression from GC-rich minimal promoter regions, including genes in the cells of the erythroid lineage (PubMed:10642511, PubMed:10828046). Represses transcription by binding to the BTE site, a GC-rich DNA element, in competition with the activator SP1. It also represses transcription by interacting with the corepressor Sin3A and HDAC1. Activates RANTES and CCL5 expression in T-cells (By similarity).INTERACTION Ubiquitous.PTM Phosphorylated by PRP4K; phosphorylation regulates its transcriptional modulator activity.SIMILARITY Belongs to the Sp1 C2H2-type zinc-finger protein family.
descriptionrecommendedName: Krueppel-like factor 13 alternativeName: Basic transcription element-binding protein 3 shortName: BTE-binding protein 3 alternativeName: Erythroid transcription factor FKLF-2 alternativeName: RANTES factor of late activated T-lymphocytes 1 shortName: RFLAT-1 alternativeName: Transcription factor BTEB3
geneNameKlf13
Bteb3
Fklf2
identifierQ9JJZ6
isSequenceChangedFALSE
keywordActivator
DNA-binding
Metal-binding
Nucleus
Phosphoprotein
Reference proteome
Repeat
Transcription
Transcription regulation
Zinc
Zinc-finger
modified[InstanceEdit:143527] Schmidt, EE, 2004-11-12 07:45:10
[InstanceEdit:217385] Schmidt, EE, 2008-03-27 06:23:53
[InstanceEdit:354386] Schmidt, EE, 2008-06-18 04:45:12
[InstanceEdit:384350] Kanapin, AA, 2008-11-26 14:00:39
[InstanceEdit:392885] Kanapin, AA, 2009-03-09 12:07:18
[InstanceEdit:400710] Schmidt, EE, 2009-03-25 05:33:35
[InstanceEdit:423310] Kanapin, AA
[InstanceEdit:435478] Kanapin, AA
[InstanceEdit:435871] Kanapin, AA
[InstanceEdit:447347] Kanapin, AA
[InstanceEdit:525883] Kanapin, AA
[InstanceEdit:613449] Kanapin, AA
[InstanceEdit:797602] Kanapin, AA
[InstanceEdit:937368] Yung, CK
[InstanceEdit:1042053] Yung, CK
[InstanceEdit:1220657] Yung, CK
[InstanceEdit:1300696] Yung, CK
[InstanceEdit:1301627] Yung, CK
[InstanceEdit:1551960] Weiser, JD
[InstanceEdit:1995863] Weiser, JD
[InstanceEdit:2132304] Weiser, JD
[InstanceEdit:2265580] Weiser, JD
[InstanceEdit:5433710] Weiser, JD
[InstanceEdit:5618415] Weiser, JD
[InstanceEdit:5634237] Weiser, JD
[InstanceEdit:5673015] Weiser, JD
[InstanceEdit:6807888] Weiser, JD
[InstanceEdit:9037114] Weiser, JD
[InstanceEdit:9637257] Weiser, JD
[InstanceEdit:9676415] Weiser, JD
[InstanceEdit:9852000] Weiser, Joel, 2023-11-03
[InstanceEdit:9917590] Weiser, Joel, 2024-08-09
nameKlf13
referenceDatabase[ReferenceDatabase:2] UniProt
secondaryIdentifierKLF13_MOUSE
Q9ESX3
Q9JHF8
sequenceLength289
species[Species:48892] Mus musculus
(referenceEntity)[EntityWithAccessionedSequence:9978116] Klf13 [nucleoplasm] [Mus musculus]
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No pathways have been reviewed or authored by UniProt:Q9JJZ6 Klf13 (93949)