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Details on Person UniProt:Q99PW8 Kif17
| Class:Id | ReferenceGeneProduct:93821 |
|---|---|
| _chainChangeLog | chain:1-1038 added on Fri February 6 2015 |
| _displayName | UniProt:Q99PW8 Kif17 |
| _timestamp | 2026-02-20 22:44:59 |
| chain | chain:1-1038 |
| checksum | 2BED852A3AFDBD46 |
| comment | FUNCTION Together with RAB23 and IFT57, it is required for the localization of specific G protein-coupled receptors, such as dopamime receptor DRD1, to primary cilia to primary cilia (By similarity). In association with the Apba1-containing complex (LIN-10-LIN-2-LIN-7 complex), transports vesicles containing N-methyl-D-aspartate (NMDA) receptor subunit NR2B along microtubules.SUBUNIT Homodimer (PubMed:10846156). Interacts with APBA1 (via PDZ domain); the interaction is direct and is required for association of KIF17 with the cargo that is to be transported (PubMed:10846156). Interacts with IFT B complex components IFT52 and IFT57 (PubMed:23810713). Interacts with IFT70B (PubMed:23810713). Interacts with PIWIL1 (PubMed:16787948). Interacts with TBATA (PubMed:17196196). Interacts with RAB23 (By similarity).INTERACTION Localizes to dendrites of pyramidal neurons (PubMed:10846156). Does not localize to the axons or nuclei in cerebral cortex, hippocampus or olfactory bulb (PubMed:10846156). Co-localizes with NR2B-containing vesicles along microtubules (PubMed:10846156).ALTERNATIVE PRODUCTS Highly expressed in the gray matter of the brain, especially in the hippocampus.DEVELOPMENTAL STAGE Expressed from embryonic day 16, and expression increases to postnatal week 3.SIMILARITY Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. |
| description | recommendedName: Kinesin-like protein KIF17 shortName: MmKIF17 |
| geneName | Kif17 |
| identifier | Q99PW8 |
| isSequenceChanged | FALSE |
| keyword | Alternative splicing ATP-binding Cell projection Coiled coil Cytoplasm Cytoskeleton Microtubule Motor protein Nucleotide-binding Protein transport Reference proteome Transport |
| modified | [InstanceEdit:143527] Schmidt, EE, 2004-11-12 07:45:10 [InstanceEdit:217385] Schmidt, EE, 2008-03-27 06:23:53 [InstanceEdit:354386] Schmidt, EE, 2008-06-18 04:45:12 [InstanceEdit:384350] Kanapin, AA, 2008-11-26 14:00:39 [InstanceEdit:392885] Kanapin, AA, 2009-03-09 12:07:18 [InstanceEdit:400710] Schmidt, EE, 2009-03-25 05:33:35 [InstanceEdit:423310] Kanapin, AA [InstanceEdit:435478] Kanapin, AA [InstanceEdit:435871] Kanapin, AA [InstanceEdit:447347] Kanapin, AA [InstanceEdit:525883] Kanapin, AA [InstanceEdit:613449] Kanapin, AA [InstanceEdit:797602] Kanapin, AA [InstanceEdit:937368] Yung, CK [InstanceEdit:1042053] Yung, CK [InstanceEdit:1220657] Yung, CK [InstanceEdit:1300696] Yung, CK [InstanceEdit:1301627] Yung, CK [InstanceEdit:1551960] Weiser, JD [InstanceEdit:1995863] Weiser, JD [InstanceEdit:2132304] Weiser, JD [InstanceEdit:2265580] Weiser, JD [InstanceEdit:2587579] Weiser, JD [InstanceEdit:3445779] Weiser, JD [InstanceEdit:5433710] Weiser, JD [InstanceEdit:5618415] Weiser, JD [InstanceEdit:5634237] Weiser, JD [InstanceEdit:5673015] Weiser, JD [InstanceEdit:8944791] Weiser, JD [InstanceEdit:9037114] Weiser, JD [InstanceEdit:9637257] Weiser, JD [InstanceEdit:9676415] Weiser, JD [InstanceEdit:9698430] Weiser, JD [InstanceEdit:9841277] Weiser, Joel [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9983091] Weiser, Joel, 2026-02-20 |
| name | Kif17 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| secondaryIdentifier | KIF17_MOUSE A2AM73 Q3V365 |
| sequenceLength | 1038 |
| species | [Species:48892] Mus musculus |
| (isoformParent) | [ReferenceIsoform:9983256] Unknown:Q99PW8-1 Kif17 [Mus musculus] [ReferenceIsoform:9983257] Unknown:Q99PW8-2 Kif17 [Mus musculus] |
| (referenceEntity) | [EntityWithAccessionedSequence:9610540] Kif17 [cytosol] [Mus musculus] |
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No pathways have been reviewed or authored by UniProt:Q99PW8 Kif17 (93821)
