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Details on Person p-IRAK2:p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane]

Class:IdComplex:937055
_displayNamep-IRAK2:p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane]
_timestamp2018-08-09 02:31:38
compartment[Compartment:876] plasma membrane
created[InstanceEdit:937065] Shamovsky, V, 2010-08-25
hasComponent
literatureReference[LiteratureReference:937049] Helical assembly in the MyD88-IRAK4-IRAK2 complex in TLR/IL-1R signalling
[LiteratureReference:571295] Identification of critical residues of the MyD88 death domain involved in the recruitment of downstream kinases
modified[InstanceEdit:1604337] Shamovsky, V, 2011-09-14
[InstanceEdit:2428907] Shamovsky, V, 2012-08-08
[InstanceEdit:8959586] Weiser, JD
[InstanceEdit:9615894] Shamovsky, Veronica, 2018-08-09
namep-IRAK2:p-IRAK4:oligo-MyD88:TIRAP:activated TLR
relatedSpecies[Species:181384] Chlamydia trachomatis
[Species:180800] Neisseria meningitidis serogroup B
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:1111633] R-HSA-937055.3
(hasComponent)[Complex:2262774] TRAF6:p-IRAK2 :p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] [Homo sapiens]
(input)[Reaction:2262777] TRAF6 binds to p-IRAK2 [Homo sapiens]
(output)[Reaction:937059] Phosphorylation of IRAK2 bound to the activated IRAK4:MyD88 oligomer:TIRAP:activated TLR complex [Homo sapiens]
(updatedInstance)[_UpdateTracker:9870641] Update Tracker - [Complex:937055] p-IRAK2:p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] - v38:[updateContainedComponent]
[_UpdateTracker:9871210] Update Tracker - [Complex:937055] p-IRAK2:p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] - v39:[updateContainedComponent]
[_UpdateTracker:9872522] Update Tracker - [Complex:937055] p-IRAK2:p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] - v41:[updateContainedComponent]
[_UpdateTracker:9873018] Update Tracker - [Complex:937055] p-IRAK2:p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] - v42:[addLiteratureReference, updateContainedComponent]
[_UpdateTracker:9874539] Update Tracker - [Complex:937055] p-IRAK2:p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] - v43:[updateContainedComponent]
[_UpdateTracker:9889391] Update Tracker - [Complex:937055] p-IRAK2:p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] - v49:[updateContainedComponent]
[_UpdateTracker:9889854] Update Tracker - [Complex:937055] p-IRAK2:p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] - v52:[updateContainedComponent]
[_UpdateTracker:9892898] Update Tracker - [Complex:937055] p-IRAK2:p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] - v54:[updateContainedComponent]
[_UpdateTracker:9895063] Update Tracker - [Complex:937055] p-IRAK2:p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] - v59:[updateContainedComponent]
[_UpdateTracker:9895997] Update Tracker - [Complex:937055] p-IRAK2:p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] - v60:[removeSpecies, updateContainedComponent]
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No pathways have been reviewed or authored by p-IRAK2:p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] (937055)
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