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Details on Person IRAK1:p-S,2T-IRAK4 :oligo-MyD88:TIRAP:activated TLR [plasma membrane]
Class:Id Complex:937018
_displayName IRAK1:p-S,2T-IRAK4 :oligo-MyD88:TIRAP:activated TLR [plasma membrane]
_timestamp 2018-08-09 02:30:03
compartment [Compartment:876] plasma membrane
created [InstanceEdit:937009] Shamovsky, V, 2010-08-25
hasComponent
literatureReference [LiteratureReference:165891] IRAK-4: a novel member of the IRAK family with the properties of an [LiteratureReference:2428820] IRAK1 and IRAK4 promote phosphorylation, ubiquitination, and degradation of MyD88 adaptor-like (Mal)
modified [InstanceEdit:1565003] Shamovsky, V, 2011-09-06 [InstanceEdit:2428905] Shamovsky, V, 2012-08-08 [InstanceEdit:8959586] Weiser, JD [InstanceEdit:9615894] Shamovsky, Veronica, 2018-08-09
name IRAK1:p-S,2T-IRAK4 :oligo-MyD88:TIRAP:activated TLR IRAK1:p-S,2T-IRAK4 :oligo-MyD88:MAL:activated TLR
relatedSpecies [Species:181384] Chlamydia trachomatis [Species:180800] Neisseria meningitidis serogroup B
species [Species:48887] Homo sapiens
stableIdentifier [StableIdentifier:1110867] R-HSA-937018.3
(input) [Reaction:166119] First phosphorylation of IRAK1 by IRAK4 bound to activated TLR:MyD88:Mal [Homo sapiens]
(physicalEntity) [CatalystActivity:937066] protein serine/threonine kinase activity of IRAK1:p-S,2T-IRAK4 :oligo-MyD88:TIRAP:activated TLR [plasma membrane]
(updatedInstance) [_UpdateTracker:9870265] Update Tracker - [Complex:937018] IRAK1:p-S,2T-IRAK4 :oligo-MyD88:TIRAP:activated TLR [plasma membrane] - v38:[modifyName, updateContainedComponent] [_UpdateTracker:9870941] Update Tracker - [Complex:937018] IRAK1:p-S,2T-IRAK4 :oligo-MyD88:TIRAP:activated TLR [plasma membrane] - v39:[updateContainedComponent] [_UpdateTracker:9871697] Update Tracker - [Complex:937018] IRAK1:p-S,2T-IRAK4 :oligo-MyD88:TIRAP:activated TLR [plasma membrane] - v41:[updateContainedComponent] [_UpdateTracker:9873229] Update Tracker - [Complex:937018] IRAK1:p-S,2T-IRAK4 :oligo-MyD88:TIRAP:activated TLR [plasma membrane] - v42:[addLiteratureReference, updateContainedComponent] [_UpdateTracker:9873879] Update Tracker - [Complex:937018] IRAK1:p-S,2T-IRAK4 :oligo-MyD88:TIRAP:activated TLR [plasma membrane] - v43:[updateContainedComponent] [_UpdateTracker:9889371] Update Tracker - [Complex:937018] IRAK1:p-S,2T-IRAK4 :oligo-MyD88:TIRAP:activated TLR [plasma membrane] - v49:[updateContainedComponent] [_UpdateTracker:9891213] Update Tracker - [Complex:937018] IRAK1:p-S,2T-IRAK4 :oligo-MyD88:TIRAP:activated TLR [plasma membrane] - v52:[updateContainedComponent] [_UpdateTracker:9892599] Update Tracker - [Complex:937018] IRAK1:p-S,2T-IRAK4 :oligo-MyD88:TIRAP:activated TLR [plasma membrane] - v54:[updateContainedComponent] [_UpdateTracker:9895640] Update Tracker - [Complex:937018] IRAK1:p-S,2T-IRAK4 :oligo-MyD88:TIRAP:activated TLR [plasma membrane] - v59:[updateContainedComponent] [_UpdateTracker:9896808] Update Tracker - [Complex:937018] IRAK1:p-S,2T-IRAK4 :oligo-MyD88:TIRAP:activated TLR [plasma membrane] - v60:[removeSpecies, updateContainedComponent]
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Protein identifiers
No pathways have been reviewed or authored by IRAK1:p-S,2T-IRAK4 :oligo-MyD88:TIRAP:activated TLR [plasma membrane] (937018)