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Details on Person K63pUb-RIP1:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane]

Class:IdComplex:937016
_displayNameK63pUb-RIP1:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane]
_timestamp2017-07-28 02:47:13
compartment[Compartment:74700] endosome membrane
created[InstanceEdit:937009] Shamovsky, V, 2010-08-25
hasComponent
literatureReference[LiteratureReference:936978] Apoptosis induced by the toll-like receptor adaptor TRIF is dependent on its receptor interacting protein homotypic interaction motif
[LiteratureReference:433849] Rip1 mediates the Trif-dependent toll-like receptor 3- and 4-induced NF-{kappa}B activation but does not contribute to interferon regulatory factor 3 activation
modified[InstanceEdit:1018390] Shamovsky, V, 2010-11-16
[InstanceEdit:1604337] Shamovsky, V, 2011-09-14
[InstanceEdit:2201362] Shamovsky, V, 2012-04-19
[InstanceEdit:2206368] Shamovsky, V, 2012-04-26
[InstanceEdit:2248858] Shamovsky, V, 2012-05-15
[InstanceEdit:2299707] Shamovsky, V, 2012-06-01
[InstanceEdit:2445248] Shamovsky, V, 2012-08-13
[InstanceEdit:9014318] Shamovsky, Veronica, 2017-07-28
nameK63pUb-RIP1:TICAM1:TRAM:TLR4:LY96:LPS:CD14
activated TLR4:TRIF:K63pUb-RIP1
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:1107346] R-HSA-937016.2
(hasComponent)[Complex:937030] CHUK:IKBKB:IKBKG:K63pUb-RIP1:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] [Homo sapiens]
(input)[Reaction:937029] IKBKG subunit of IKK complex binds polyubiquinated RIP1 [Homo sapiens]
(output)[Reaction:168915] K63-linked ubiquitination of RIP1 bound to the activated TLR complex [Homo sapiens]
(regulator)[NegativeRegulation:2569044] Negative regulation by 'K63pUb-RIP1:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane]'
(updatedInstance)[_UpdateTracker:9871358] Update Tracker - [Complex:937016] K63pUb-RIP1:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] - v39:[updateContainedComponent]
[_UpdateTracker:9872279] Update Tracker - [Complex:937016] K63pUb-RIP1:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] - v41:[add_removeCompartment, add_removeHasComponent, modifyName, removeSpecies, updateContainedComponent]
[_UpdateTracker:9873076] Update Tracker - [Complex:937016] K63pUb-RIP1:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] - v42:[addLiteratureReference, modifyName, updateContainedComponent]
[_UpdateTracker:9875297] Update Tracker - [Complex:937016] K63pUb-RIP1:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] - v44:[updateContainedComponent]
[_UpdateTracker:9890443] Update Tracker - [Complex:937016] K63pUb-RIP1:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] - v52:[updateContainedComponent]
[_UpdateTracker:9892703] Update Tracker - [Complex:937016] K63pUb-RIP1:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] - v54:[updateContainedComponent]
[_UpdateTracker:9897731] Update Tracker - [Complex:937016] K63pUb-RIP1:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] - v62:[add_removeHasComponent, modifyName, removeLiteratureReference]
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No pathways have been reviewed or authored by K63pUb-RIP1:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (937016)
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