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Details on Person Activated PP2A dephosphorylates phosphorylated Sprouty2

Class:IdReaction:934600
_displayNameActivated PP2A dephosphorylates phosphorylated Sprouty2
_timestamp2016-07-15 23:50:11
authored[InstanceEdit:934560] Williams, MG, 2010-08-17
catalystActivity[CatalystActivity:934603] protein serine/threonine phosphatase activity of PP2A (A:C):Y55/S112/S121/Y227-phospho Sprouty 2 [plasma membrane]
compartment[Compartment:70101] cytosol
[Compartment:876] plasma membrane
created[InstanceEdit:934557] Williams, MG, 2010-08-17
figure[Figure:947911] /figures/DrosRasRafERKA93.jpg
input[Complex:934619] PP2A (A:C):Y55/S112/S121/Y227-phospho Sprouty 2 [plasma membrane] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:934564] Direct binding of PP2A to Sprouty2 and phosphorylation changes are a prerequisite for ERK inhibition downstream of fibroblast growth factor receptor stimulation
modified[InstanceEdit:947706] Williams, MG, 2010-09-13
[InstanceEdit:947989] Williams, MG, 2010-09-14
[InstanceEdit:1043153] Wu, G, 2010-11-19
[InstanceEdit:8879177] Wu, G, 2016-07-15
nameActivated PP2A dephosphorylates phosphorylated Sprouty2
output[Complex:934598] PP2A(A:C):Y55/Y227-pSPRY2 [plasma membrane] [Homo sapiens]
[SimpleEntity:29372] Pi [cytosol]
[SimpleEntity:29372] Pi [cytosol]
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:8913978] R-HSA-934600.1
summation[Summation:934579] In humans, activated Ser/Thr protein phosphatase PP2A dephos...
(hasEvent)[Pathway:481001] Ras/Raf/ERK pathway - Inferred Events
(inferredFrom)[Reaction:934621] Activated PP2A dephosphorylates phosphorylated STY [Drosophila melanogaster]
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No pathways have been reviewed or authored by Activated PP2A dephosphorylates phosphorylated Sprouty2 (934600)
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