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Details on Person Ubiquitinated phosphorylated Sprouty2 is degraded by the 26S proteasome

Class:IdBlackBoxEvent:934585
_displayNameUbiquitinated phosphorylated Sprouty2 is degraded by the 26S proteasome
_timestamp2016-07-15 23:50:28
authored[InstanceEdit:934560] Williams, MG, 2010-08-17
catalystActivity[CatalystActivity:68824] endopeptidase activity of 26S proteasome [cytosol]
compartment[Compartment:876] plasma membrane
created[InstanceEdit:934557] Williams, MG, 2010-08-17
figure[Figure:947923] /figures/DrosRasRafERKA105.jpg
input[Complex:934572] Ub:Y55/Y227-pSPRY2:CBL [plasma membrane] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:188630] Sprouty fine-tunes EGF signaling through interlinked positive and negative feedback loops
[LiteratureReference:183004] hSpry2 is targeted to the ubiquitin-dependent proteasome pathway by c-Cbl
modified[InstanceEdit:947865] Williams, MG, 2010-09-14
[InstanceEdit:947989] Williams, MG, 2010-09-14
[InstanceEdit:8879177] Wu, G, 2016-07-15
nameUbiquitinated phosphorylated Sprouty2 is degraded by the 26S proteasome
output[EntityWithAccessionedSequence:112199] CBL [cytosol] [Homo sapiens]
[DefinedSet:113595] Ub [cytosol] [Homo sapiens]
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:8920825] R-HSA-934585.1
summation[Summation:934575] In humans, the ubiquitinated phosphorylated adaptor protein ...
(hasEvent)[Pathway:481001] Ras/Raf/ERK pathway - Inferred Events
(inferredFrom)[BlackBoxEvent:934563] Ubiquitinated phosphorylated STY is degraded by the 26S proteasome [Drosophila melanogaster]
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