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Details on Person UniProt:Q9JIP3 Il17rb
Class:Id
ReferenceGeneProduct:92718
_chainChangeLog
signal peptide:1-17 added on Fri February 6 2015;chain:18-499 added on Fri February 6 2015
_displayName
UniProt:Q9JIP3 Il17rb
_timestamp
2023-11-03 15:48:30
chain
signal peptide:1-17 chain:18-499
checksum
C66440430E3C31F3
comment
FUNCTION Receptor for the pro-inflammatory cytokines IL17B and IL17E. May play a role in controlling the growth and/or differentiation of hematopoietic cells.SUBUNIT Interacts with DAZAP2. Interacts with TRAF3IP2.SUBCELLULAR LOCATION Liver and testis. Expressed at lower level in kidney and lung. Expressed in selected T-cell, B-cell and myeloid cell lines.MISCELLANEOUS Evi27 is a common site of retroviral integration in Bxh2 murine myeloid leukemias, localized near the Il17rb gene. Proviral integrations result in increased expression of Il17rb on the cell surface.