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Details on Person p-STAT5 dissociates from the receptor complex

Class:Id	Reaction:921155
_displayName	p-STAT5 dissociates from the receptor complex
_doRelease	TRUE
_timestamp	2017-03-23 17:06:34
authored	[InstanceEdit:744679] Ray, KP, 2010-05-17
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:921154] Jupe, S, 2010-08-05
edited	[InstanceEdit:927712] Jupe, S, 2010-08-06
input	[DefinedSet:913465] High affinity binding complex dimers of cytokine receptors using Bc, activated JAK2:p-STAT5 [plasma membrane] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:919407] A single STAT recruitment module in a chimeric cytokine receptor complex is sufficient for STAT activation
modified	[InstanceEdit:921159] Jupe, S, 2010-08-05 [InstanceEdit:927713] Jupe, S, 2010-08-06 [InstanceEdit:939147] Jupe, S, 2010-08-31 [InstanceEdit:941871] Jupe, S, 2010-09-06 [InstanceEdit:1043153] Wu, G, 2010-11-19 [InstanceEdit:8983468] Jupe, Steve, 2017-03-23 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	p-STAT5 dissociates from the receptor complex
output	[DefinedSet:913405] High affinity binding complex dimers of cytokine receptors using Bc, activated JAK2 [plasma membrane] [Homo sapiens] [DefinedSet:507929] p-STAT5A, p-STAT5B [cytosol] [Homo sapiens] [DefinedSet:507929] p-STAT5A, p-STAT5B [cytosol] [Homo sapiens] [DefinedSet:507929] p-STAT5A, p-STAT5B [cytosol] [Homo sapiens]
precedingEvent	[Reaction:879909] Activation of STAT5a/b by JAK2 [Homo sapiens] [Reaction:879930] STAT5 is recruited by JAK2 [Homo sapiens]
releaseDate	2010-09-21
reviewed	[InstanceEdit:941869] Lopez, AF, 2010-09-06 [InstanceEdit:941867] Hercus, TR, 2010-09-06
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:1104151] R-HSA-921155.3
summation	[Summation:919408] Deletion mutants have demonstrated that STAT dimerization ca...
(hasEvent)	[Pathway:512988] Interleukin-3, Interleukin-5 and GM-CSF signaling [Homo sapiens]
(precedingEvent)	[Reaction:452102] p-STAT5 dimerizes [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9790012] Update Tracker - [Reaction:921155] p-STAT5 dissociates from the receptor complex - v36:[modifyText]
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No pathways have been reviewed or authored by p-STAT5 dissociates from the receptor complex (921155)