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Details on Person Phosphorylated STAT5 is released

Class:Id	Reaction:919404
_displayName	Phosphorylated STAT5 is released
_doRelease	TRUE
_timestamp	2017-12-08 18:23:23
authored	[InstanceEdit:744679] Ray, KP, 2010-05-17
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:919403] Jupe, S, 2010-08-04
edited	[InstanceEdit:924611] Jupe, S, 2010-08-06
input	[Complex:507943] IL2:IL2R trimer p-(Y338,Y392, Y510) beta subunit:p-JAK1:JAK3:p-STAT5 [plasma membrane] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:919407] A single STAT recruitment module in a chimeric cytokine receptor complex is sufficient for STAT activation
modified	[InstanceEdit:919411] Jupe, S, 2010-08-04 [InstanceEdit:926765] Jupe, S, 2010-08-06 [InstanceEdit:939149] Jupe, S, 2010-08-31 [InstanceEdit:941874] Jupe, S, 2010-09-06 [InstanceEdit:1043153] Wu, G, 2010-11-19 [InstanceEdit:1168657] Jupe, S, 2011-01-05 [InstanceEdit:1213499] Jupe, S, 2011-02-11 [InstanceEdit:1233244] Jupe, S, 2011-03-17 [InstanceEdit:1248024] Jupe, S, 2011-04-11 [InstanceEdit:9020559] Duenas, Corina, 2017-09-07 [InstanceEdit:9032271] Orlic-Milacic, Marija, 2017-12-08 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Phosphorylated STAT5 is released
output	[Complex:452119] IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] [Homo sapiens] [DefinedSet:507929] p-STAT5A, p-STAT5B [cytosol] [Homo sapiens]
precedingEvent	[Reaction:452097] Recruited STAT5 is phosphorylated [Homo sapiens] [Reaction:452108] Phosphorylation of IL2RB Y338, Y392 or Y510 enables STAT recruitment [Homo sapiens]
releaseDate	2011-03-15
reviewed	[InstanceEdit:1213492] Villarino, A, 2011-02-11 [InstanceEdit:1233246] Dooms, H, 2011-03-17
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:1225076] R-HSA-919404.4
summation	[Summation:919408] Deletion mutants have demonstrated that STAT dimerization ca...
(hasEvent)	[Pathway:9020558] Interleukin-2 signaling [Homo sapiens]
(precedingEvent)	[Reaction:452102] p-STAT5 dimerizes [Homo sapiens]
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No pathways have been reviewed or authored by Phosphorylated STAT5 is released (919404)