Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Details on Person Recruitment of IRF3,IRF7

Class:Id	Reaction:918232
_displayName	Recruitment of IRF3,IRF7
_doRelease	TRUE
_timestamp	2023-05-18 15:05:17
authored	[InstanceEdit:918228] Garapati, P V, 2010-08-02
compartment	[Compartment:70101] cytosol [Compartment:17906] mitochondrial outer membrane
created	[InstanceEdit:918228] Garapati, P V, 2010-08-02
edited	[InstanceEdit:918228] Garapati, P V, 2010-08-02
input	[DefinedSet:450317] IRF3,IRF7 [cytosol] [Homo sapiens] [Complex:9710999] viral dsRNA:IFIH1, viral dsRNA:K63polyUb-DDX58:MAVS:K63polyUb-TRAF3:2x(TBK1/IKBKE) [mitochondrial outer membrane] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:166859] IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway [LiteratureReference:918176] VISA is an adapter protein required for virus-triggered IFN-beta signaling [LiteratureReference:918216] Distinct functions of IRF-3 and IRF-7 in IFN-alpha gene regulation and control of anti-tumor activity in primary macrophages
modified	[InstanceEdit:933522] Garapati, P V, 2010-08-16 [InstanceEdit:933545] Garapati, P V, 2010-08-16 [InstanceEdit:990524] Garapati, P V, 2010-11-03 [InstanceEdit:994081] Garapati, P V, 2010-11-05 [InstanceEdit:998145] Garapati, P V, 2010-11-09 [InstanceEdit:1022090] Garapati, P V, 2010-11-17 [InstanceEdit:1043153] Wu, G, 2010-11-19 [InstanceEdit:8983918] Jupe, Steve, 2017-03-31 [InstanceEdit:9014715] Shamovsky, Veronica, 2017-08-02 [InstanceEdit:9031715] D'Eustachio, Peter, 2017-12-01 [InstanceEdit:9031726] D'Eustachio, Peter, 2017-12-01 [InstanceEdit:9715437] Shamovsky, Veronica, 2021-02-17 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9835846] Shamovsky, Veronica, 2023-05-18
name	Recruitment of IRF3,IRF7
output	[Complex:918199] viral dsRNA:IFIH1, viral dsRNA:K63polyUb-DDX58:MAVS:K63polyUb-TRAF3:2xTBK1,IKBKE:IRF3,IRF7 [mitochondrial outer membrane] [Homo sapiens]
precedingEvent	[Reaction:918225] TBK1/IKK epsilon complex interacts with MAVS bound TRAF3 [Homo sapiens] [Reaction:918227] Recruitment of TRAF3 to MAVS [Homo sapiens]
relatedSpecies	[Species:5621375] Hepatitis C Virus [Species:9013948] Measles virus [Species:5617433] Rotavirus [Species:9031716] Influenza A virus [Species:9717528] Human respiratory syncytial virus A
releaseDate	2010-12-14
reviewed	[InstanceEdit:990527] Kawai, T, Akira, S, 2010-10-30
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:1105034] R-HSA-918232.6
summation	[Summation:918168] IRF3 and IRF7 (IRF3/IRF7) are the two major members of the i...
(hasEvent)	[Pathway:918233] TRAF3-dependent IRF activation pathway [Homo sapiens]
(inferredFrom)	[Reaction:1227863] Recruitment of IRF to activated TBK1/IKK epsilon [Gallus gallus]
(precedingEvent)	[Reaction:918229] Phosphorylation and release of IRF3/IRF7 [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9776459] Update Tracker - [Reaction:918232] Recruitment of IRF3,IRF7 - v76:[add_removeInput] [_UpdateTracker:9928470] Update Tracker - [Reaction:918232] Recruitment of IRF3,IRF7 - v91:[modifyText]
[Change default viewing format]

No pathways have been reviewed or authored by Recruitment of IRF3,IRF7 (918232)