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Details on Person VISA is an adapter protein required for virus-triggered IFN-beta signaling

Class:IdLiteratureReference:918176
_displayNameVISA is an adapter protein required for virus-triggered IFN-beta signaling
_timestamp2010-08-02 08:28:18
author[Person:918151] Xu, LG
[Person:918170] Wang, YY
[Person:918171] Han, KJ
[Person:141905] Li, LY
[Person:918157] Zhai, Z
[Person:918155] Shu, HB
created[InstanceEdit:918172] Garapati, P V, 2010-08-02
journalMol Cell
pages727-40
pubMedIdentifier16153868
titleVISA is an adapter protein required for virus-triggered IFN-beta signaling
volume19
year2005
(literatureReference)[Reaction:168909] viral dsRNA:IFIH1, viral dsRNA:K63polyUb-DDX58 bind MAVS [Homo sapiens]
[Reaction:918230] Recruitment of TRAF6/TRAF2 to MAVS [Homo sapiens]
[Reaction:918232] Recruitment of IRF3,IRF7 [Homo sapiens]
[Reaction:1227709] Activated MDA5 binds IPS-1 [Gallus gallus]
[Reaction:1227775] TRAF6/or TRAF2 interacts with IPS-1 [Gallus gallus]
[Reaction:1227863] Recruitment of IRF to activated TBK1/IKK epsilon [Gallus gallus]
[Reaction:1227891] TRAF3/or TRAF6 interacts with IPS-1 [Gallus gallus]
[Pathway:1227892] TRAF6 mediated NF-kB activation [Gallus gallus]
[Summation:918168] IRF3 and IRF7 (IRF3/IRF7) are the two major members of the i...
[Summation:1237376] In mammals, the response to viral infection is mediated thro...
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