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Details on Person Mitochondrial antiviral-signaling protein (MAVS or IPS-1) in...
| Class:Id | Summation:918169 |
|---|---|
| _displayName | Mitochondrial antiviral-signaling protein (MAVS or IPS-1) in... |
| _timestamp | 2024-11-05 11:21:52 |
| created | [InstanceEdit:918172] Garapati, P V, 2010-08-02 |
| literatureReference | [LiteratureReference:918288] VISA--a pass to innate immunity |
| modified | [InstanceEdit:918289] Garapati, P V, 2010-08-03 [InstanceEdit:992759] Garapati, P V, 2010-11-04 [InstanceEdit:9927236] Shamovsky, Veronica, 2024-11-05 |
| text | Mitochondrial antiviral-signaling protein (MAVS or IPS-1) interacts with TRAF2 and TRAF6 through its consensus TRAF-interaction motif (TIM) (TRAF2 143-PVGET-147 and TRAF6 153-PGENSE-158 & 455-PEENEY-460). Although MAVS (IPS-1) can bind to both TRAF6 and TRAF2, TRAF2 binding is not required for MAVS activation of NF-kappaB. |
| (summation) | [Reaction:918230] Recruitment of TRAF6/TRAF2 to MAVS [Homo sapiens] |
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No pathways have been reviewed or authored by Mitochondrial antiviral-signaling protein (MAVS or IPS-1) in... (918169)
