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Details on Person SLC46A1 transports hemes from extracellular region to cytosol

Class:Id	Reaction:917870
_displayName	SLC46A1 transports hemes from extracellular region to cytosol
_doRelease	TRUE
_timestamp	2021-01-25 11:29:26
authored	[InstanceEdit:917791] Stephan, R, 2010-07-01
catalystActivity	[CatalystActivity:917906] heme transmembrane transporter activity of SLC46A1 [plasma membrane]
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:917843] Jassal, Bijay, 2010-07-30
edited	[InstanceEdit:917843] Jassal, Bijay, 2010-07-30
input	[CandidateSet:9707310] Hemes [extracellular region]
isChimeric	FALSE
literatureReference	[LiteratureReference:917859] Identification of an intestinal heme transporter
modified	[InstanceEdit:983711] Jassal, Bijay, 2010-11-02 [InstanceEdit:984583] Jassal, Bijay, 2010-11-02 [InstanceEdit:994086] Jassal, Bijay, 2010-11-05 [InstanceEdit:5691161] Jassal, Bijay, 2015-05-05 [InstanceEdit:9707309] Stephan, Ralf, 2020-11-16 [InstanceEdit:9707852] Stephan, Ralf, 2020-11-20 [InstanceEdit:9713328] Stephan, Ralf, 2021-01-25 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	SLC46A1 transports hemes from extracellular region to cytosol Extracellular ferriheme uptake through the apical membrane of enterocytes
output	[CandidateSet:9707308] Hemes [cytosol]
releaseDate	2010-12-14
reviewed	[InstanceEdit:994085] D'Eustachio, P, 2010-11-05 [InstanceEdit:9713327] Somers, Julia, 2021-01-23
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:1104483] R-HSA-917870.4
summation	[Summation:917897] Uptake of iron from meat happens mostly in the form of ferri...
(hasEvent)	[Pathway:917937] Iron uptake and transport [Homo sapiens] [Pathway:9707616] Heme signaling [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9776304] Update Tracker - [Reaction:917870] SLC46A1 transports hemes from extracellular region to cytosol - v76:[modifyText] [_UpdateTracker:9776633] Update Tracker - [Reaction:917870] SLC46A1 transports hemes from extracellular region to cytosol - v75:[add_removeInput, add_removeOutput, modifyText]
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