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Details on Person Acidification of Tf:TfR1 containing endosome

Class:Id	Reaction:917841
_displayName	Acidification of Tf:TfR1 containing endosome
_doRelease	TRUE
_timestamp	2016-03-01 09:35:26
authored	[InstanceEdit:917973] Stephan, R, 2010-07-13
catalystActivity	[CatalystActivity:912612] proton transmembrane transporter activity of V-ATPase:ATP6AP1 [endosome membrane]
compartment	[Compartment:74700] endosome membrane
created	[InstanceEdit:917843] Jassal, Bijay, 2010-07-30
edited	[InstanceEdit:917843] Jassal, Bijay, 2010-07-30
input	[SimpleEntity:113592] ATP [cytosol] [SimpleEntity:70106] H+ [cytosol] [SimpleEntity:70106] H+ [cytosol] [SimpleEntity:70106] H+ [cytosol] [SimpleEntity:29356] H2O [cytosol]
isChimeric	FALSE
literatureReference	[LiteratureReference:917911] Coupling of rotation and catalysis in F(1)-ATPase revealed by single-molecule imaging and manipulation
modified	[InstanceEdit:984583] Jassal, Bijay, 2010-11-02 [InstanceEdit:994086] Jassal, Bijay, 2010-11-05 [InstanceEdit:8862716] Jassal, Bijay, 2016-03-01 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Acidification of Tf:TfR1 containing endosome
output	[SimpleEntity:29370] ADP [cytosol] [SimpleEntity:29372] Pi [cytosol] [SimpleEntity:74722] H+ [endosome lumen] [SimpleEntity:74722] H+ [endosome lumen] [SimpleEntity:74722] H+ [endosome lumen]
precedingEvent	[BlackBoxEvent:917807] holoTF:TFRC dimer translocates from plasma membrane to endosome membrane [Homo sapiens] [Reaction:917987] TFRC dimer binds 2xholoTF [Homo sapiens]
releaseDate	2010-12-14
reviewed	[InstanceEdit:994085] D'Eustachio, P, 2010-11-05
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:1105395] R-HSA-917841.3
summation	[Summation:917890] The function of V-type proton pumping ATPases is basically t...
(hasEvent)	[Pathway:917977] Transferrin endocytosis and recycling [Homo sapiens]
(precedingEvent)	[Reaction:917835] Fe3+ dissociates from holoTF:TFRC dimer [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9788672] Update Tracker - [Reaction:917841] Acidification of Tf:TfR1 containing endosome - v41:[modifyText] [_UpdateTracker:9788811] Update Tracker - [Reaction:917841] Acidification of Tf:TfR1 containing endosome - v40:[modifyText] [_UpdateTracker:9789824] Update Tracker - [Reaction:917841] Acidification of Tf:TfR1 containing endosome - v37:[modifyText]
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