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Details on Person GCNT3 transfers GlcNAc to Core 3 mucin

Class:Id	Reaction:914018
_displayName	GCNT3 transfers GlcNAc to Core 3 mucin
_doRelease	TRUE
_timestamp	2025-04-08 08:41:25
authored	[InstanceEdit:913626] Jassal, B, 2010-07-19
catalystActivity	[CatalystActivity:976831] beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity of GCNT3 [Golgi membrane]
compartment	[Compartment:20699] Golgi membrane [Compartment:17963] Golgi lumen
created	[InstanceEdit:914014] Jassal, B, 2010-07-21
crossReference	[DatabaseIdentifier:9942403] RHEA:56189 [DatabaseIdentifier:9942399] RHEA:56193
edited	[InstanceEdit:913626] Jassal, B, 2010-07-19
input	[DefinedSet:1462159] Core 3 mucins [Golgi lumen] [Homo sapiens] [SimpleEntity:914003] UDP-GlcNAc [Golgi lumen]
isChimeric	FALSE
literatureReference	[LiteratureReference:977025] Molecular cloning and expression of a novel beta-1, 6-N-acetylglucosaminyltransferase that forms core 2, core 4, and I branches [LiteratureReference:977072] Control of O-glycan branch formation. Molecular cloning of human cDNA encoding a novel beta1,6-N-acetylglucosaminyltransferase forming core 2 and core 4
modified	[InstanceEdit:976828] Jassal, B, 2010-10-14 [InstanceEdit:977066] Jassal, B, 2010-10-15 [InstanceEdit:981828] Jassal, B, 2010-10-27 [InstanceEdit:1043153] Wu, G, 2010-11-19 [InstanceEdit:1462326] Wu, G, 2011-07-28 [InstanceEdit:1963546] Jassal, B, 2011-11-03 [InstanceEdit:1963553] Jassal, B, 2011-11-03 [InstanceEdit:1964511] Jassal, B, 2011-11-04 [InstanceEdit:1965758] Jassal, B, 2011-11-04 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9942394] Stephan, Ralf, 2025-03-16 [InstanceEdit:9944934] Stephan, Ralf, 2025-04-08
name	GCNT3 transfers GlcNAc to Core 3 mucin Addition of GlcNAc to Core 3 forms a Core 4 glycoprotein
output	[DefinedSet:1462144] Core 4 mucins [Golgi lumen] [Homo sapiens] [SimpleEntity:205687] UDP [Golgi lumen] [SimpleEntity:425969] H+ [Golgi lumen]
precedingEvent	[Reaction:914010] B3GNT6 transfers GlcNAc to Tn antigen [Homo sapiens] [Reaction:913675] GALNTs transfer GalNAc to Mucins to form Tn antigens [Homo sapiens]
previousReviewStatus	[ReviewStatus:9821384] two stars
releaseDate	2011-12-06
reviewed	[InstanceEdit:1964508] Ferrer, A, 2011-11-04 [InstanceEdit:9944933] D'Eustachio, Peter, 2025-04-08
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:2016120] R-HSA-914018.3
structureModified	[InstanceEdit:9942394] Stephan, Ralf, 2025-03-16
summation	[Summation:977076] The glycosyltransferase GCNT3 mediates core 2 and core 4 O-g...
(hasEvent)	[Pathway:913709] O-linked glycosylation of mucins [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9953725] Update Tracker - [Reaction:914018] GCNT3 transfers GlcNAc to Core 3 mucin - v93:[removeOutput]
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No pathways have been reviewed or authored by GCNT3 transfers GlcNAc to Core 3 mucin (914018)