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Details on Person Translocation of p-STAT1:p-STAT1 dimer to nucleus

Class:Id	Reaction:913529
_displayName	Translocation of p-STAT1:p-STAT1 dimer to nucleus
_doRelease	TRUE
_timestamp	2021-11-03 00:30:51
authored	[InstanceEdit:909728] Garapati, P V, 2010-07-07
compartment	[Compartment:13231] nuclear envelope
created	[InstanceEdit:913530] Garapati, P V, 2010-07-16
edited	[InstanceEdit:909728] Garapati, P V, 2010-07-07
input	[Complex:9757480] p-Y701-STAT1:KPNA1:KPNB1 [cytosol] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:873866] Interferon activation of the transcription factor Stat91 involves dimerization through SH2-phosphotyrosyl peptide interactions
modified	[InstanceEdit:918223] Garapati, P V, 2010-08-02 [InstanceEdit:933346] Garapati, P V, 2010-08-10 [InstanceEdit:933763] Garapati, P V, 2010-08-17 [InstanceEdit:941856] Garapati, P V, 2010-09-06 [InstanceEdit:994080] Garapati, P V, 2010-11-05 [InstanceEdit:998148] Garapati, P V, 2010-11-09 [InstanceEdit:9710985] Shamovsky, Veronica, 2021-01-06 [InstanceEdit:9731169] Shamovsky, Veronica, 2021-05-13 [InstanceEdit:9736379] Shamovsky, Veronica, 2021-07-07 [InstanceEdit:9751161] Shamovsky, Veronica, 2021-08-18 [InstanceEdit:9757503] Shamovsky, Veronica, 2021-11-01 [InstanceEdit:9757617] Shamovsky, Veronica, 2021-11-03 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Translocation of p-STAT1:p-STAT1 dimer to nucleus
output	[Complex:913526] p-Y701-STAT1 dimer [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:188865] KPNA1 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:180714] KPNB1 [nucleoplasm] [Homo sapiens]
precedingEvent	[Reaction:9710963] p-STAT1dimer:KPNA1 binds KPNB1 [Homo sapiens] [Reaction:9710959] p-STAT1 dimer binds KPNA1 [Homo sapiens]
releaseDate	2010-12-14
requiredInputComponent	[Complex:157689] Nuclear Pore Complex (NPC) [nuclear envelope] [Homo sapiens]
reviewed	[InstanceEdit:933762] Abdul-Sater, AA, Schindler, C, 2010-08-17
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:1105359] R-HSA-913529.6
summation	[Summation:913514] IFNA-activated-factor (AAF) translocates to nucleus and then...
(hasEvent)	[Pathway:909733] Interferon alpha/beta signaling [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9775490] Update Tracker - [Reaction:913529] Translocation of p-STAT1:p-STAT1 dimer to nucleus - v79:[addOutput, add_removeInput] [_UpdateTracker:9776148] Update Tracker - [Reaction:913529] Translocation of p-STAT1:p-STAT1 dimer to nucleus - v77:[removeRegulator] [_UpdateTracker:9776401] Update Tracker - [Reaction:913529] Translocation of p-STAT1:p-STAT1 dimer to nucleus - v76:[addRegulator]
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