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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

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Details on Person RAPGEF1 [cytosol]

Class:IdEntityWithAccessionedSequence:913472
_displayNameRAPGEF1 [cytosol]
_timestamp2016-06-07 19:52:56
compartment[Compartment:70101] cytosol
created[InstanceEdit:913471] Jupe, S, 2010-07-14
endCoordinate1077
modified[InstanceEdit:3132750] Wu, G, 2013-02-13
[InstanceEdit:3448660] Wu, G, 2013-05-16
[InstanceEdit:8875562] Orlic-Milacic, Marija, 2016-06-07
nameRAPGEF1
Rap guanine nucleotide exchange factor 1
RPGF1_HUMAN
C3G
referenceEntity[ReferenceGeneProduct:405669] UniProt:Q13905 RAPGEF1 [Homo sapiens]
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:1111812] R-HSA-913472.2
startCoordinate1
(activeUnit)[CatalystActivity:8875567] guanyl-nucleotide exchange factor activity of HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL:RAPGEF1 [plasma membrane]
(hasCandidate)[CandidateSet:9020391] RAC3 effectors [cytosol] [Homo sapiens]
(hasComponent)[Complex:190070] Active TrkA receptor:p-FRS2:CRKL:RAPGEF1 [endosome membrane] [Homo sapiens]
[Complex:372643] RAPGEF1:Crk [plasma membrane] [Homo sapiens]
[Complex:381957] PDGF:Phospho-PDGF receptor dimer:Crk:p130Cas:C3G [plasma membrane] [Homo sapiens]
[Complex:914209] p(Y700,731,774)-CBL:CRK:RAPGEF1 [cytosol] [Homo sapiens]
[Complex:8875561] HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL:RAPGEF1 [plasma membrane] [Homo sapiens]
[Complex:9024734] CRKL:RAPGEF1 [cytosol] [Homo sapiens]
[Complex:9024740] p-CRKL:RAPGEF1 [cytosol] [Homo sapiens]
(input)[Reaction:170978] p-FRS2:CRKL binds C3G [Homo sapiens]
[Reaction:382052] p130Cas and C3G bind PDGFR bound Crk [Homo sapiens]
[Reaction:912734] CBL:CRKL binds RAPGEF1 [Homo sapiens]
[Reaction:8875558] RAPGEF1 binds CRK,CRKL [Homo sapiens]
(replacementInstances)[_Deleted:9763808] Deletion of instance: 3008672
[_Deleted:9763810] Deletion of instance: 3008672
(updatedInstance)[_UpdateTracker:9877486] Update Tracker - [EntityWithAccessionedSequence:913472] RAPGEF1 [cytosol] - v44:[modifyEndCoordinate]
[_UpdateTracker:9894988] Update Tracker - [EntityWithAccessionedSequence:913472] RAPGEF1 [cytosol] - v58:[addName]
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No pathways have been reviewed or authored by RAPGEF1 [cytosol] (913472)