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Details on Person Jupe, S, 2010-07-14
| Class:Id | InstanceEdit:913398 |
| _displayName | Jupe, S, 2010-07-14 |
| _timestamp | 2010-07-14 16:23:05 |
| author | [Person:391309] Jupe, Steve |
| dateTime | 2010-07-14 20:18:19 |
| (created) | [Person:913353] Jordan, SR [EntityWithAccessionedSequence:913354] INPPL1 [cytosol] [Homo sapiens] [Complex:913355] GM-CSF:GM-CSF receptor alpha subunit:p(Y593, 628)-Bc:JAK2 [plasma membrane] [Homo sapiens] [Summation:913356] Phosphorylation of Shc at three tyrosine residues, 239, 240 ... [Complex:913357] IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] [Homo sapiens] [Complex:913358] IL3:IL3R active complex, inactive JAK2, phosphorylated Bc:SHC1 [plasma membrane] [Homo sapiens] [Complex:913359] High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] [Homo sapiens] [Reaction:913360] GM-CSF receptor alpha subunit binds GM-CSF [Homo sapiens] [EntityWithAccessionedSequence:913361] CSF2RA [plasma membrane] [Homo sapiens] [Complex:913362] GM-CSF:GM-CSF receptor alpha subunit [plasma membrane] [Homo sapiens] |
| (modified) | [Reaction:450031] Interleukin-3 receptor alpha: Interleukin-3 binds IL3RB:JAK2 [Homo sapiens] [Complex:450056] IL5 homodimer:IL5RA [plasma membrane] [Homo sapiens] [Pathway:512988] Interleukin-3, Interleukin-5 and GM-CSF signaling [Homo sapiens] [Summation:561111] The Interleukin-3 (IL-3), IL-5 and Granulocyte-macrophage co... [Reaction:879907] Tyrosine kinases phosphorylate the receptor [Homo sapiens] [Reaction:879909] Activation of STAT5a/b by JAK2 [Homo sapiens] [Reaction:879910] JAK2 is phosphorylated, activated [Homo sapiens] [Reaction:879922] Mouse JAK2 binds human common beta chain [Homo sapiens] [Reaction:879925] SHC1 bound to the common beta chain becomes tyrosine phosphorylated [Homo sapiens] [Reaction:879930] STAT5 is recruited by JAK2 [Homo sapiens] |
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No pathways have been reviewed or authored by Jupe, S, 2010-07-14 (913398)