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Details on Person Jupe, S, 2010-07-09
| Class:Id | InstanceEdit:912563 |
| _displayName | Jupe, S, 2010-07-09 |
| _timestamp | 2010-07-09 14:57:24 |
| author | [Person:391309] Jupe, Steve |
| dateTime | 2010-07-09 18:57:04 |
| (created) | [LiteratureReference:912558] Fyn associates with Cbl and phosphorylates tyrosine 731 in Cbl, a binding site for phosphatidylinositol 3-kinase [Summation:912559] CBL is tyrosine phosphorylated following stimulation with IL... [LiteratureReference:912560] The proto-oncogene product c-Cbl becomes tyrosine phosphorylated by stimulation with GM-CSF or Epo and constitutively binds to the SH3 domain of Grb2/Ash in human hematopoietic cells [LiteratureReference:912561] Phosphorylation of Cbl following stimulation with interleukin-3 and its association with Grb2, Fyn, and phosphatidylinositol 3-kinase [Summation:912562] CBL phosphorylation at Y731 is postulated to provide an addi... [Person:912565] Mitani, K [Person:912566] Koch, BL [Person:912567] Hanazono, Y [Person:912568] Odai, H [Person:912569] Burton, EA |
| (modified) | [BlackBoxEvent:453104] Phosphorylated SHC1 recruits GRB2:GAB2 [Homo sapiens] [Reaction:453111] Phosphorylated SHC recruits GRB2:SOS1 [Homo sapiens] [Reaction:879917] CBL, GRB2, FYN and PI3K p85 subunit are constitutively associated [Homo sapiens] [Pathway:912526] Interleukin receptor SHC signaling [Homo sapiens] |
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No pathways have been reviewed or authored by Jupe, S, 2010-07-09 (912563)