Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Details on Person Formation of meiotic single-stranded DNA invasion complex

Class:Id	BlackBoxEvent:912503
_displayName	Formation of meiotic single-stranded DNA invasion complex
_doRelease	TRUE
_timestamp	2024-05-16 11:55:14
authored	[InstanceEdit:913923] May, B, 2010-07-19
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:912491] May, B, 2010-07-08
edited	[InstanceEdit:913923] May, B, 2010-07-19
inferredFrom	[BlackBoxEvent:912421] Formation of Meiotic Single-stranded Invasion Complex [Mus musculus]
input	[EntityWithAccessionedSequence:50951] BRCA2 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:62637] RAD51 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:912490] DMC1 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:69484] ATM [nucleoplasm] [Homo sapiens] [Complex:68462] RPA heterotrimer [nucleoplasm] [Homo sapiens] [OtherEntity:75156] 3' overhanging DNA at resected DSB ends [nucleoplasm] [EntityWithAccessionedSequence:50949] BRCA1 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:113843] CDK4 [nucleoplasm] [Homo sapiens] [Complex:975775] H2AFX-Nucleosome [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:913210] Temporal progression of recombination in human males [LiteratureReference:913242] Structure of the hDmc1-ssDNA filament reveals the principles of its architecture [LiteratureReference:913259] A comparative analysis of Dmc1 and Rad51 nucleoprotein filaments [LiteratureReference:913251] The meiosis-specific recombinase hDmc1 forms ring structures and interacts with hRad51 [LiteratureReference:913234] Human meiotic recombinase Dmc1 promotes ATP-dependent homologous DNA strand exchange [LiteratureReference:913202] Interactions between human BRCA2 protein and the meiosis-specific recombinase DMC1 [LiteratureReference:913318] Analysis of replication protein A (RPA) in human spermatogenesis [LiteratureReference:83639] Interaction of human rad51 recombination protein with single-stranded DNA binding protein, RPA. [LiteratureReference:913262] Distribution of the Rad51 recombinase in human and mouse spermatocytes [LiteratureReference:265961] Association of BRCA1 with Rad51 in mitotic and meiotic cells
modified	[InstanceEdit:913297] May, B, 2010-07-13 [InstanceEdit:914114] May, B, 2010-07-22 [InstanceEdit:914224] May, B, 2010-07-24 [InstanceEdit:975789] May, B, 2010-10-04 [InstanceEdit:1008999] May, B, 2010-11-11 [InstanceEdit:1017214] May, B, 2010-11-16 [InstanceEdit:1086964] May, B, 2010-11-29 [InstanceEdit:1220550] May, B, 2011-02-20 [InstanceEdit:1221624] May, B, 2011-02-25 [InstanceEdit:5255525] May, B, 2014-02-06 [InstanceEdit:9023950] May, Bruce, 2017-09-29 [InstanceEdit:9606200] Wu, G, 2018-04-19 [InstanceEdit:9641190] Wu, G, 2019-04-04 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9910665] Orlic-Milacic, Marija, 2024-05-16
name	Formation of meiotic single-stranded DNA invasion complex Formation of Early Recombination Nodule
negativePrecedingEvent	[NegativePrecedingEvent:9910664] Futile Cycle: Formation of meiotic holliday junction [NegativePrecedingEvent:9910661] Futile Cycle: Resolution of meiotic holliday junction
output	[Complex:912507] Meiotic single-stranded DNA complex [nucleoplasm] [Homo sapiens]
precedingEvent	[BlackBoxEvent:9023943] MRN:CtIP exonucleolytically hydrolyzes DNA 3' to SPO11 and SPO11:double-strand break dissociates to SPO11:oligonucleotide and resected 5' end [Homo sapiens] [BlackBoxEvent:9023941] MRN:CtIP endonucleolytically cleaves single-strand DNA 3' to SPO11 [Homo sapiens]
regulatedBy	[PositiveRegulation:914161] Positive regulation by 'TEX15 [nucleoplasm]' [PositiveRegulation:914162] Positive regulation by 'RAD51C [nucleoplasm]'
regulationReference	[RegulationReference:9641572] Positive regulation by 'RAD51C [nucleoplasm]' RAD51C deficiency in mice results in early prophase I arrest in males and sister chromatid separation at metaphase II in females [RegulationReference:9643003] Positive regulation by 'TEX15 [nucleoplasm]' Mouse TEX15 is essential for DNA double-strand break repair and chromosomal synapsis during male meiosis
releaseDate	2011-03-15
reviewed	[InstanceEdit:1221628] Bolcun-Filas, E, 2011-02-25 [InstanceEdit:1181360] Cohen, PE, 2011-02-04 [InstanceEdit:1181371] Holloway, JK, 2011-02-04 [InstanceEdit:1221625] Lyndaker, A, 2011-02-25 [InstanceEdit:1181380] Schimenti, JC, 2011-02-04 [InstanceEdit:1221623] Strong, E, 2011-02-25
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:1224921] R-HSA-912503.6
summation	[Summation:914103] Two RecA homologs, RAD51 and the meiosis-specific DMC1, coat...
(hasEvent)	[Pathway:912446] Meiotic recombination [Homo sapiens]
(precedingEvent)	[BlackBoxEvent:912458] Formation of meiotic heteroduplex [Homo sapiens]
[Change default viewing format]

No pathways have been reviewed or authored by Formation of meiotic single-stranded DNA invasion complex (912503)