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Details on Person Resolution of meiotic holliday junction

Class:Id	BlackBoxEvent:912429
_displayName	Resolution of meiotic holliday junction
_doRelease	TRUE
_timestamp	2014-02-06 18:11:13
authored	[InstanceEdit:912374] May, B, 2010-07-02
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:912491] May, B, 2010-07-08
edited	[InstanceEdit:912374] May, B, 2010-07-02
inferredFrom	[BlackBoxEvent:912487] Resolution of Meiotic Holliday Junction [Mus musculus]
input	[Complex:912428] Meiotic Holliday Junction [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:912495] MLH1 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:912478] MLH3 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:68365] CDK2 [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:913758] MSH4 acts in conjunction with MLH1 during mammalian meiosis [LiteratureReference:913902] Crossing over analysis at pachytene in man [LiteratureReference:914218] Expression of the MutL homologue hMLH3 in human cells and its role in DNA mismatch repair [LiteratureReference:913210] Temporal progression of recombination in human males [LiteratureReference:914137] The interacting domains of three MutL heterodimers in man: hMLH1 interacts with 36 homologous amino acid residues within hMLH3, hPMS1 and hPMS2
modified	[InstanceEdit:913297] May, B, 2010-07-13 [InstanceEdit:913736] May, B, 2010-07-19 [InstanceEdit:914114] May, B, 2010-07-22 [InstanceEdit:914224] May, B, 2010-07-24 [InstanceEdit:975789] May, B, 2010-10-04 [InstanceEdit:1008999] May, B, 2010-11-11 [InstanceEdit:1022078] May, B, 2010-11-17 [InstanceEdit:1086964] May, B, 2010-11-29 [InstanceEdit:1181379] May, B, 2011-02-07 [InstanceEdit:1220550] May, B, 2011-02-20 [InstanceEdit:1221624] May, B, 2011-02-25 [InstanceEdit:5255525] May, B, 2014-02-06 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Resolution of meiotic holliday junction
output	[Complex:913201] Cleaved Meiotic Holliday Junction [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:912455] MSH4 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:912435] MSH5 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:50951] BRCA2 [nucleoplasm] [Homo sapiens] [Complex:68462] RPA heterotrimer [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:174881] BLM [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:912452] TOP3A [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:113843] CDK4 [nucleoplasm] [Homo sapiens]
precedingEvent	[BlackBoxEvent:912496] Formation of meiotic holliday junction [Homo sapiens] [BlackBoxEvent:912458] Formation of meiotic heteroduplex [Homo sapiens]
releaseDate	2011-03-15
reviewed	[InstanceEdit:1221628] Bolcun-Filas, E, 2011-02-25 [InstanceEdit:1181360] Cohen, PE, 2011-02-04 [InstanceEdit:1181371] Holloway, JK, 2011-02-04 [InstanceEdit:1221625] Lyndaker, A, 2011-02-25 [InstanceEdit:1181380] Schimenti, JC, 2011-02-04 [InstanceEdit:1221623] Strong, E, 2011-02-25
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:1224967] R-HSA-912429.2
summation	[Summation:914153] Meiotic Holliday junctions are cleaved to yield either cross...
(hasEvent)	[Pathway:912446] Meiotic recombination [Homo sapiens]
(precedingEvent)	[NegativePrecedingEvent:9910660] Futile Cycle: Resolution of meiotic holliday junction [NegativePrecedingEvent:9910661] Futile Cycle: Resolution of meiotic holliday junction
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No pathways have been reviewed or authored by Resolution of meiotic holliday junction (912429)