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Details on Person Prdm9 Binds Recombination Hotspot Motifs in DNA

Class:Id	Reaction:912383
_displayName	Prdm9 Binds Recombination Hotspot Motifs in DNA
_doRelease	TRUE
_timestamp	2011-03-02 09:10:51
authored	[InstanceEdit:912374] May, B, 2010-07-02
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:912369] May, B, 2010-07-08
edited	[InstanceEdit:912374] May, B, 2010-07-02
input	[EntityWithAccessionedSequence:912359] Prdm9 [nucleoplasm] [Mus musculus] [OtherEntity:29428] DNA [nucleoplasm]
isChimeric	FALSE
literatureReference	[LiteratureReference:912339] PRDM9 is a major determinant of meiotic recombination hotspots in humans and mice [LiteratureReference:913222] Prdm9 controls activation of mammalian recombination hotspots [LiteratureReference:1181361] A mouse speciation gene encodes a meiotic histone H3 methyltransferase [LiteratureReference:1181362] A histone H3 methyltransferase controls epigenetic events required for meiotic prophase
modified	[InstanceEdit:913297] May, B, 2010-07-13 [InstanceEdit:914114] May, B, 2010-07-22 [InstanceEdit:1008999] May, B, 2010-11-11 [InstanceEdit:1086964] May, B, 2010-11-29 [InstanceEdit:1181379] May, B, 2011-02-07 [InstanceEdit:1220550] May, B, 2011-02-20 [InstanceEdit:1221624] May, B, 2011-02-25 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Prdm9 Binds Recombination Hotspot Motifs in DNA
output	[Complex:912364] PRDM9:DNA Complex [nucleoplasm] [Mus musculus]
precedingEvent	[BlackBoxEvent:912355] Telomere clustering at the nuclear membrane [Mus musculus] [BlackBoxEvent:912362] Formation of Axial/Lateral Elements of Synaptonemal Complex [Mus musculus]
releaseDate	2011-03-15
reviewed	[InstanceEdit:1221628] Bolcun-Filas, E, 2011-02-25 [InstanceEdit:1181360] Cohen, PE, 2011-02-04 [InstanceEdit:1181371] Holloway, JK, 2011-02-04 [InstanceEdit:1221625] Lyndaker, A, 2011-02-25 [InstanceEdit:1181380] Schimenti, JC, 2011-02-04 [InstanceEdit:1221623] Strong, E, 2011-02-25
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48892] Mus musculus
stableIdentifier	[StableIdentifier:1224985] R-MMU-912383.2
summation	[Summation:914147] The Prdm9 protein binds to sequences that are hotspots for r...
(inferredFrom)	[Reaction:912363] PRDM9 binds recombination hotspot motifs in DNA [Homo sapiens]
(precedingEvent)	[Reaction:1214198] Prdm9 Trimethylates Histone H3 at Lysine-4 [Mus musculus]
(replacementInstances)	[_Deleted:9032440] Deletion of instance: 5334727 [_Deleted:9032441] Deletion of instance: 912497
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No pathways have been reviewed or authored by Prdm9 Binds Recombination Hotspot Motifs in DNA (912383)