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Details on Person Incorrectly folded glycoproteins translocate to the ERQC

Class:Id	Reaction:912291
_displayName	Incorrectly folded glycoproteins translocate to the ERQC
_doRelease	TRUE
_timestamp	2010-12-02 14:33:52
authored	[InstanceEdit:749521] Dall'Olio, GM, 2009-11-10
compartment	[Compartment:17957] endoplasmic reticulum lumen [Compartment:927893] endoplasmic reticulum quality control compartment
created	[InstanceEdit:912293] Jassal, B, 2010-07-08
edited	[InstanceEdit:912293] Jassal, B, 2010-07-08
input	[Complex:909547] (un)folded protein:(GlcNAc)2 (Man)9 [endoplasmic reticulum lumen] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:941858] N-glycan structure dictates extension of protein folding or onset of disposal
modified	[InstanceEdit:916859] Jassal, B, 2010-07-29 [InstanceEdit:927894] Jassal, B, 2010-08-10 [InstanceEdit:933772] Jassal, B, 2010-08-17 [InstanceEdit:941857] Jassal, B, 2010-09-06 [InstanceEdit:1022125] Jassal, B, 2010-11-17 [InstanceEdit:1031644] Jassal, B, 2010-11-18 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Incorrectly folded glycoproteins translocate to the ERQC
output	[Complex:912283] (un)folded protein:(GlcNAc)2 (Man)9 [endoplasmic reticulum quality control compartment] [Homo sapiens]
precedingEvent	[Reaction:548890] Removal of the third glucose by glucosidase II and release from the chaperone [Homo sapiens] [Reaction:901047] Binding of ERp57 [Homo sapiens]
releaseDate	2010-09-21
reviewed	[InstanceEdit:933773] Gagneux, P, 2010-08-17
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:1104419] R-HSA-912291.2
summation	[Summation:912282] Proteins with folding defects get transported to the Endopla...
(hasEvent)	[Pathway:901042] Calnexin/calreticulin cycle [Homo sapiens]
(precedingEvent)	[Reaction:901074] MAN1B1,EDEM2 hydrolyse 1,2-linked mannose (b branch) [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9790116] Update Tracker - [Reaction:912291] Incorrectly folded glycoproteins translocate to the ERQC - v35:[modifyText]
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No pathways have been reviewed or authored by Incorrectly folded glycoproteins translocate to the ERQC (912291)