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Details on Person beta-alanine + pyruvate => 3-oxopropanoate + alanine

Class:Id	Reaction:909776
_displayName	beta-alanine + pyruvate => 3-oxopropanoate + alanine
_doRelease	TRUE
_timestamp	2025-12-11 22:36:12
authored	[InstanceEdit:909782] D'Eustachio, P, 2010-07-07
catalystActivity	[CatalystActivity:909784] beta-alanine:pyruvate transaminase activity of AGXT2 tetramer [mitochondrial matrix]
compartment	[Compartment:5460] mitochondrial matrix
created	[InstanceEdit:909782] D'Eustachio, P, 2010-07-07
crossReference	[DatabaseIdentifier:9976505] RHEA:14079
edited	[InstanceEdit:909782] D'Eustachio, P, 2010-07-07
inferredFrom	[Reaction:909762] beta-alanine + pyruvate => 3-oxopropanoate + alanine [Rattus norvegicus]
input	[SimpleEntity:909777] b-Ala [mitochondrial matrix] [SimpleEntity:113557] PYR [mitochondrial matrix]
isChimeric	FALSE
literatureReference	[LiteratureReference:904862] Human alanine-glyoxylate aminotransferase 2 lowers asymmetric dimethylarginine and protects from inhibition of nitric oxide production
modified	[InstanceEdit:909790] D'Eustachio, P, 2010-07-07 [InstanceEdit:941848] Garapati, P V, 2010-09-04 [InstanceEdit:996691] D'Eustachio, P, 2010-11-07 [InstanceEdit:1004537] D'Eustachio, P, 2010-11-09 [InstanceEdit:1080820] D'Eustachio, P, 2010-11-27 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9976516] D'Eustachio, Peter, 2025-12-11
name	beta-alanine + pyruvate => 3-oxopropanoate + alanine beta-alanine + pyruvate => 3-oxopropanoate + L-alanine
output	[SimpleEntity:909783] OPROP [mitochondrial matrix] [SimpleEntity:379697] L-Ala [mitochondrial matrix]
precedingEvent	[BlackBoxEvent:909765] Mitochondrial uptake of beta-alanine [Homo sapiens] [Reaction:73591] conversion of 3-ureidopropionate to beta-alanine [Homo sapiens]
releaseDate	2010-12-14
reviewed	[InstanceEdit:1004534] Jassal, B, 2010-11-09
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:1105244] R-HSA-909776.3
summation	[Summation:909769] Mitochondrial AGXT2 tetramer catalyzes the reaction of beta-...
(hasEvent)	[Pathway:73621] Pyrimidine catabolism [Homo sapiens]
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No pathways have been reviewed or authored by beta-alanine + pyruvate => 3-oxopropanoate + alanine (909776)