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Details on Person Formation of Shc-Grb2 complexes is necessary to induce neoplastic transformation by overexpression of Shc proteins

Class:IdLiteratureReference:909736
_displayNameFormation of Shc-Grb2 complexes is necessary to induce neoplastic transformation by overexpression of Shc proteins
_timestamp2010-07-07 16:51:03
author[Person:183049] Salcini, AE
[Person:379122] McGlade, J
[Person:188606] Pelicci, G
[Person:909743] Nicoletti, I
[Person:181821] Pawson, T
[Person:188611] Pelicci, PG
created[InstanceEdit:909735] Jupe, S, 2010-07-07
journalOncogene
modified[InstanceEdit:909752] Jupe, S, 2010-07-07
pages2827-36
pubMedIdentifier8084588
titleFormation of Shc-Grb2 complexes is necessary to induce neoplastic transformation by overexpression of Shc proteins
volume9
year1994
(literatureReference)[BlackBoxEvent:453104] Phosphorylated SHC1 recruits GRB2:GAB2 [Homo sapiens]
[Reaction:879891] Phosphorylated Shc binds to Grb2 in the Grb2:Gab2 complex [Homo sapiens]
[Reaction:879925] SHC1 bound to the common beta chain becomes tyrosine phosphorylated [Homo sapiens]
[Summation:909742] IL-3, IL-5 and GM-CSF all induce tyrosine phosphorylation of...
[Summation:913356] Phosphorylation of Shc at three tyrosine residues, 239, 240 ...
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