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Details on Person Formation of p-STAT1 homodimer

Class:IdReaction:909718
_displayNameFormation of p-STAT1 homodimer
_doReleaseTRUE
_timestamp2019-05-06 17:47:44
authored[InstanceEdit:909728] Garapati, P V, 2010-07-07
catalystActivity[CatalystActivity:909727] protein tyrosine kinase activity of IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:p-STAT2 [plasma membrane]
catalystActivityReference[CatalystActivityReference:9644164] protein tyrosine kinase activity of IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:p-STAT2 [plasma membrane] A protein tyrosine kinase in the interferon alpha/beta signaling pathway
compartment[Compartment:70101] cytosol
[Compartment:876] plasma membrane
created[InstanceEdit:909728] Garapati, P V, 2010-07-07
edited[InstanceEdit:909728] Garapati, P V, 2010-07-07
input[SimpleEntity:113592] ATP [cytosol]
[SimpleEntity:113592] ATP [cytosol]
[EntityWithAccessionedSequence:380745] STAT1-1 [cytosol] [Homo sapiens]
[EntityWithAccessionedSequence:380745] STAT1-1 [cytosol] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:873866] Interferon activation of the transcription factor Stat91 involves dimerization through SH2-phosphotyrosyl peptide interactions
modified[InstanceEdit:913528] Garapati, P V, 2010-07-16
[InstanceEdit:918223] Garapati, P V, 2010-08-02
[InstanceEdit:933346] Garapati, P V, 2010-08-10
[InstanceEdit:933763] Garapati, P V, 2010-08-17
[InstanceEdit:941856] Garapati, P V, 2010-09-06
[InstanceEdit:994080] Garapati, P V, 2010-11-05
[InstanceEdit:998146] Garapati, P V, 2010-11-09
[InstanceEdit:1043153] Wu, G, 2010-11-19
[InstanceEdit:5604944] Garapati, P V, 2014-07-02
[InstanceEdit:9033585] Orlic-Milacic, Marija, 2017-12-22
[InstanceEdit:9645178] Orlic-Milacic, Marija, 2019-05-06
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameFormation of p-STAT1 homodimer
output[SimpleEntity:29370] ADP [cytosol]
[SimpleEntity:29370] ADP [cytosol]
[Complex:913524] p-Y701-STAT1-1 dimer [cytosol] [Homo sapiens]
precedingEvent
releaseDate2010-12-14
reviewed[InstanceEdit:933762] Abdul-Sater, AA, Schindler, C, 2010-08-17
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:1104781] R-HSA-909718.4
summation[Summation:909668] Under certain conditions type I IFNs, IFNA/B are able to act...
(hasEvent)[Pathway:909733] Interferon alpha/beta signaling [Homo sapiens]
(precedingEvent)[Reaction:9710959] p-STAT1 dimer binds KPNA1 [Homo sapiens]
(updatedInstance)[_UpdateTracker:9785997] Update Tracker - [Reaction:909718] Formation of p-STAT1 homodimer - v50:[removeInput, removeOutput]
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No pathways have been reviewed or authored by Formation of p-STAT1 homodimer (909718)
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