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Details on Person IFNA/B:IFNAR2:p-JAK1:STAT2:IFNAR1:p-TYK2 [plasma membrane]

Class:Id	Complex:909705
_displayName	IFNA/B:IFNAR2:p-JAK1:STAT2:IFNAR1:p-TYK2 [plasma membrane]
_timestamp	2010-12-02 14:51:08
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:909716] Garapati, P V, 2010-07-07
hasComponent	[Complex:909707] IFNAR1:p-TYK2 [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:877334] IFNAR1 [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:909682] p-Y1054,Y1055-TYK2 [cytosol] [Homo sapiens] [Complex:909692] IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] [Homo sapiens] [DefinedSet:909690] IFN alpha/beta (IFNA/B) [extracellular region] [Homo sapiens] [Complex:909715] IFNAR2:p-JAK1:STAT2 [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:877333] IFNAR2-2 [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:882029] STAT2 [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:451921] p-Y-JAK1 [cytosol] [Homo sapiens]
isChimeric	FALSE
modified	[InstanceEdit:918194] Garapati, P V, 2010-08-02
name	IFNA/B:IFNAR2:p-JAK1:STAT2:IFNAR1:p-TYK2
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:1108291] R-HSA-909705.1
(input)	[Reaction:909730] Phosphorylation of INFAR1 by TYK2 [Homo sapiens] [Reaction:997311] Dephosphorylation of TYK2 by PTP1B [Homo sapiens]
(output)	[Reaction:909729] Activation of JAK kinases [Homo sapiens]
(physicalEntity)	[CatalystActivity:909723] protein tyrosine kinase activity of IFNA/B:IFNAR2:p-JAK1:STAT2:IFNAR1:p-TYK2 [plasma membrane]
(updatedInstance)	[_UpdateTracker:9984806] Update Tracker - [Complex:909705] IFNA/B:IFNAR2:p-JAK1:STAT2:IFNAR1:p-TYK2 [plasma membrane] - v96:[updateContainedComponent]
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No pathways have been reviewed or authored by IFNA/B:IFNAR2:p-JAK1:STAT2:IFNAR1:p-TYK2 [plasma membrane] (909705)