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Details on Person Jupe, S, 2010-07-02
| Class:Id | InstanceEdit:904809 |
| _displayName | Jupe, S, 2010-07-02 |
| _timestamp | 2010-07-02 15:51:30 |
| author | [Person:391309] Jupe, Steve |
| dateTime | 2010-07-02 19:50:28 |
| (created) | [LiteratureReference:904797] In vitro interaction between STAT 5 and JAK 2; dependence upon phosphorylation status of STAT 5 and JAK 2 [LiteratureReference:904798] Functional subdomains of STAT2 required for preassociation with the alpha interferon receptor and for signaling [Summation:904799] Upon receptor activation, Shc is recruited to the receptor c... [LiteratureReference:904800] Signaling functions of the tyrosine residues in the betac chain of the granulocyte-macrophage colony-stimulating factor receptor [CatalystActivity:904801] protein tyrosine kinase activity of Tyrosine kinases that phosphorylate the Common beta chain [plasma membrane] [Person:904802] Foster, R [LiteratureReference:904803] Suppression of interleukin-3-induced gene expression by a C-terminal truncated Stat5: role of Stat5 in proliferation [Person:904804] Gustafsson, JA [Person:904805] Wakao, H [LiteratureReference:904806] A novel cytokine-inducible gene CIS encodes an SH2-containing protein that binds to tyrosine-phosphorylated interleukin 3 and erythropoietin receptors |
| (modified) | [Pathway:512988] Interleukin-3, Interleukin-5 and GM-CSF signaling [Homo sapiens] [Summation:561111] The Interleukin-3 (IL-3), IL-5 and Granulocyte-macrophage co... [Reaction:879907] Tyrosine kinases phosphorylate the receptor [Homo sapiens] [Reaction:879909] Activation of STAT5a/b by JAK2 [Homo sapiens] [Reaction:879910] JAK2 is phosphorylated, activated [Homo sapiens] [Summation:879913] The interaction of IL-3 with the receptor leads to the activ... [BlackBoxEvent:879923] SRC is activated [Homo sapiens] [Reaction:879925] SHC1 bound to the common beta chain becomes tyrosine phosphorylated [Homo sapiens] [Reaction:879934] Recruitment of SHC1 is mediated by Y593 of the common beta chain [Homo sapiens] [Summation:879946] Upon ligand binding to the alpha subunit, the alpha and Bc s... |
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No pathways have been reviewed or authored by Jupe, S, 2010-07-02 (904809)