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Details on Person UniProt:P49772 Flt3lg
Class:Id
ReferenceGeneProduct:90469
_chainChangeLog
signal peptide:1-26 added on Fri February 6 2015;chain:27-232 added on Fri February 6 2015
_displayName
UniProt:P49772 Flt3lg
_timestamp
2025-02-21 19:48:01
chain
signal peptide:1-26 chain:27-232
checksum
3A3680D3CB69FBA6
comment
FUNCTION Stimulates the proliferation of early hematopoietic cells by activating FLT3. Synergizes well with a number of other colony stimulating factors and interleukins. Essential for the development of natural killer (NK) cells, B cells, and dendritic cells (DCs).SUBUNIT Homodimer (soluble isoform).SUBCELLULAR LOCATION Biologically active.SUBCELLULAR LOCATION Inactive.