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Details on Person IFIH1 ligand [cytosol]

Class:Id	DefinedSet:9038422
_displayName	IFIH1 ligand [cytosol]
_timestamp	2023-05-13 07:22:38
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9038421] Shamovsky, Veronica, 2018-02-26
disease	[Disease:3134794] viral infectious disease
goCellularComponent	[Compartment:436407] host cell cytosol
hasMember	[GenomeEncodedEntity:9013943] MV dsRNA intermediate form [cytosol] [Measles virus] [GenomeEncodedEntity:6790580] Influenza A dsRNA intermediate form [cytosol] [Influenza A virus] [GenomeEncodedEntity:9835308] RSV A dsRNA intermediate form [cytosol] [Human respiratory syncytial virus A]
literatureReference	[LiteratureReference:9013945] The interferon-inducible RNA helicase, mda-5, is involved in measles virus-induced expression of antiviral cytokines
modified	[InstanceEdit:9658105] Weiser, JD, 2019-08-09 [InstanceEdit:9658105] Weiser, JD, 2019-08-09 [InstanceEdit:9666277] Weiser, JD, 2019-11-04 [InstanceEdit:9666277] Weiser, JD, 2019-11-04 [InstanceEdit:9676538] Cook, Justin, 2020-02-17 [InstanceEdit:9676538] Cook, Justin, 2020-02-17 [InstanceEdit:9689079] Cook, Justin, 2020-05-15 [InstanceEdit:9689079] Cook, Justin, 2020-05-15 [InstanceEdit:9715688] Shorser, Solomon, 2021-02-17 [InstanceEdit:9729976] Shorser, Solomon, 2021-05-05 [InstanceEdit:9750461] Weiser, JD, 2021-08-11 [InstanceEdit:9757984] Weiser, JD, 2021-11-08 [InstanceEdit:9767390] Wright, Adam, 2022-02-25 [InstanceEdit:9773515] Weiser, Joel, 2022-05-04 [InstanceEdit:9835310] Stephan, Ralf, 2023-05-13 [InstanceEdit:9909910] Weiser, Joel, 2024-05-14 [InstanceEdit:9917728] Weiser, Joel, 2024-08-09 [InstanceEdit:9926726] Weiser, Joel, 2024-11-03 [InstanceEdit:9939161] Weiser, Joel, 2025-02-21 [InstanceEdit:9948552] Weiser, Joel, 2025-05-21 [InstanceEdit:9963749] Weiser, Joel, 2025-08-15 [InstanceEdit:9970792] Weiser, Joel, 2025-10-31 [InstanceEdit:9983308] Weiser, Joel, 2026-02-22 [InstanceEdit:9989150] Weiser, Joel, 2026-05-15
name	IFIH1 ligand MDA5 ligand
species	[Species:9013948] Measles virus [Species:9031716] Influenza A virus [Species:9717528] Human respiratory syncytial virus A
stableIdentifier	[StableIdentifier:9038423] R-NUL-9038422.20
(hasComponent)	[Complex:913727] viral dsRNA:IFIH1 [cytosol] [Homo sapiens] [Complex:9733908] viral dsRNA:IFIH1:ZCCHC3 [cytosol] [Homo sapiens] [Complex:9733944] viral dsRNA:IFIH1:YWHAH [cytosol] [Homo sapiens]
(input)	[Reaction:913725] viral dsRNA binds IFIH1:TKFC [Homo sapiens] [Reaction:9717627] ZCCHC3 binds viral dsRNA and IFIH1:DAK [Homo sapiens]
(replacementInstances)	[_Deleted:9038427] Deletion of instance: 9013950
(updatedInstance)	[_UpdateTracker:9905899] Update Tracker - [DefinedSet:9038422] IFIH1 ligand [cytosol] - v85:[addHasMember, addSpecies]
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No pathways have been reviewed or authored by IFIH1 ligand [cytosol] (9038422)