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Details on Person UniProt:P54130 Fgf9
Class:Id
ReferenceGeneProduct:90382
_chainChangeLog
propeptide:1-3 added on Sat February 7 2015;chain:4-208 added on Sat February 7 2015
_displayName
UniProt:P54130 Fgf9
_timestamp
2023-11-03 15:16:48
chain
propeptide:1-3 chain:4-208
checksum
4A3CE894DFF643EB
comment
FUNCTION Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. May have a role in glial cell growth and differentiation during development, gliosis during repair and regeneration of brain tissue after damage, differentiation and survival of neuronal cells, and growth stimulation of glial tumors.SUBUNIT Monomer. Homodimer. Interacts with FGFR1, FGFR2, FGFR3 and FGFR4. Affinity between fibroblast growth factors (FGFs) and their receptors is increased by heparan sulfate glycosaminoglycans that function as coreceptors (By similarity).SUBCELLULAR LOCATION Belongs to the heparin-binding growth factors family.
