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Details on Person MyD88 variant:TIRAP:BTK:activated TLR2/4 [plasma membrane]

Class:IdComplex:9037685
_displayNameMyD88 variant:TIRAP:BTK:activated TLR2/4 [plasma membrane]
_timestamp2019-08-14 18:24:47
compartment[Compartment:876] plasma membrane
created[InstanceEdit:9037686] Shamovsky, Veronica, 2018-02-20
disease[Disease:5228860] primary immunodeficiency disease
hasComponent
modified[InstanceEdit:9615894] Shamovsky, Veronica, 2018-08-09
[InstanceEdit:9658481] Shamovsky, Veronica, 2019-08-14
nameMyD88 variant:TIRAP:BTK:activated TLR2/4
MyD88 variant:MAL:BTK:activated TLR2/4
relatedSpecies[Species:181384] Chlamydia trachomatis
[Species:180800] Neisseria meningitidis serogroup B
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9037687] R-HSA-9037685.3
(diseaseEntity)[EntityFunctionalStatus:9658483] loss_of_function of MyD88 variant:TIRAP:BTK:activated TLR2/4 [plasma membrane]
(input)[FailedReaction:5602383] Defective MyD88 does not oligomerize within the activated TLR2/4 complex [Homo sapiens]
(updatedInstance)[_UpdateTracker:9899475] Update Tracker - [Complex:9037685] MyD88 variant:TIRAP:BTK:activated TLR2/4 [plasma membrane] - v66:[addName, updateContainedComponent]
[_UpdateTracker:9899669] Update Tracker - [Complex:9037685] MyD88 variant:TIRAP:BTK:activated TLR2/4 [plasma membrane] - v67:[updateContainedComponent]
[_UpdateTracker:9900837] Update Tracker - [Complex:9037685] MyD88 variant:TIRAP:BTK:activated TLR2/4 [plasma membrane] - v70:[addDisease]
[_UpdateTracker:9902094] Update Tracker - [Complex:9037685] MyD88 variant:TIRAP:BTK:activated TLR2/4 [plasma membrane] - v76:[updateContainedComponent]
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No pathways have been reviewed or authored by MyD88 variant:TIRAP:BTK:activated TLR2/4 [plasma membrane] (9037685)
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