Query author contributions in Reactome
Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.
If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.
Details on Person The histo-blood group ABO system transferase (ABO) is the ba...
| Class:Id | Summation:9037573 |
|---|---|
| _displayName | The histo-blood group ABO system transferase (ABO) is the ba... |
| _timestamp | 2018-05-02 15:08:15 |
| created | [InstanceEdit:9037574] Jassal, Bijay, 2018-02-19 |
| modified | [InstanceEdit:9037613] Jassal, Bijay, 2018-02-20 [InstanceEdit:9607312] Jassal, Bijay, 2018-05-02 |
| text | The histo-blood group ABO system transferase (ABO) is the basis of the ABO blood group system. A, B and AB individuals express glycosyltransferase activity that converts the H antigen to the A antigen (by addition of GalNAc), to the B antigen (by addition of Gal) or to the AB antigen (by the addition of both GalNAc and Gal). O group individuals lack such activity. Differences in four critical amino acids (176, 235, 266 and 268) alter the specificity from an A to a B glycosyltransferase (Yamamoto et al. 1990, Yamamoto & McNeill 1996, Seto et al. 1999, Alfaro et al. 2008). The histo-blood group B transferase (ABO-B) utilises UDP-Gal to transfer galactose (Gal) to the H antigen formed via Type 2 chains to form the B antigen (Patenaude et al. 2002, Persson et al. 2007). |
| (summation) | [Reaction:9033961] ABO-B:Mn2+ transfers Gal to H antigen-RBC to form B antigen-RBC [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by The histo-blood group ABO system transferase (ABO) is the ba... (9037573)
